Category: Research Article

Application of latent semantic indexing to evaluate the similarity of sets of sequences without multiple alignments character-by-character

B.R.G.M. Couto, A.P. Ladeira, M.A. SantosPublished October 05, 2007Genet. Mol. Res. 6 (4): 983-999 (2007) About the authorsB.R.G.M. Couto, A.P. Ladeira, M.A. Santos Corresponding authorB.R.G.M. CoutoE-mail: bcouto@acad.unibh.br ABSTRACT Most molecular analyses, including phylogenetic inference, are based on sequence alignments. We present an algorithm that estimates relatedness between biomolecules without the requirement of sequence alignment by […]

A simple genetic algorithm for multiple sequence alignment

C. Gondro, B.P. KinghornPublished October 05, 2007Genet. Mol. Res. 6 (4): 964-982 (2007) About the authorsC. Gondro, B.P. Kinghorn Corresponding authorC. GondroE-mail: cgondro2@une.edu.au ABSTRACT Multiple sequence alignment plays an important role in molecular sequence analysis. An alignment is the arrangement of two (pairwise alignment) or more (multiple alignment) sequences of ‘residues’ (nucleotides or amino acids) […]

Prediction and biochemical characterization ofintrinsic disorder in the structure of proteolysis inducing factor/dermcidin

G. Majczak, S. Lilla*,M. Garay-Malpartida, J. Markovic,F.J. Medrano, G. de Nucci, J.E. BelizárioPublished October 5, 2007Genet. Mol. Res. 6 (4): 1000-1011 (2007) About the authorsG. Majczak, S. Lilla*,M. Garay-Malpartida, J. Markovic,F.J. Medrano, G. de Nucci, J.E. Belizário Corresponding authorJ.E. BelizárioE-mail: jebeliza@usp.br ABSTRACT Proteolysis-inducing factor/dermcidin (PIF/DCD) is a novel human gene, located on chromosome 12, locus […]

Study of genetic divergence among wheat genotypesthrough random amplified polymorphic DNA

A. Iqbal, A.S. Khan, I.A. Khan, F.S. Awan, A. Ahmad, A.A. KhanPublished August 7, 2007Genet. Mol. Res. 6 (3): 476-481 (2007) About the authorsA. Iqbal, A.S. Khan, I.A. Khan, F.S. Awan, A. Ahmad, A.A. Khan Corresponding authorF.S. AwanE-mail: awanfaisal@yahoo.com ABSTRACT The degree of genetic divergence was estimated in seven wheat genotypes, six exotic genotypes and […]

Estimation of genetic parameters and variance components for growth traits in Romosinuano cattle in the Colombian humid tropics

R.M. Sarmiento, J.P. GarciaPublished August 7, 2007Genet. Mol. Res. 6 (3): 482-491 (2007) About the authorsR.M. Sarmiento, J.P. Garcia Corresponding authorR.M. SarmientoE-mail: rodrigomartinez19@yahoo.com   ABSTRACT (Co)variance components and genetic parameters were estimated for body weights of a Romosinuano herd located in Sinú Valley, Cordoba, Colombia. Restricted maximum likelihood methods were used with a univariate animal […]

Evolutionary tree reconstruction using structuralexpectation maximization and homotopy

J. Li, M. GuoPublished September 5, 2007Genet. Mol. Res. 6 (3): 522-533 (2007) About the authorsJ. Li, M. Guo Corresponding authoJ. LiE-mail: lijianfu@hit.edu.cn or jianfu_lili@163.com ABSTRACT The evolutionary tree reconstruction algorithm called SEMPHY using structural expectation maximization (SEM) is an efficient approach but has local optimality problem. To improve SEMPHY, a new algorithm named HSEMPHY […]

Prevalence of vitamin D receptor gene polymorphism in a Uruguayan population and its relation to type 1 diabetes mellitus

A. Mimbacas, J. Trujillo, C. Gascue, G. Javiel, H. CardosoPublished September 5, 2007Genet. Mol. Res. 6 (3): 534-542(2007) About the authorsA. Mimbacas, J. Trujillo, C. Gascue, G. Javiel, H. Cardoso Corresponding authoA. MimbacasE-mail: abmg@iibce.edu.uy ABSTRACT Vitamin D has important immuno-modulatory properties and it influences insulin secretion. It acts through a vitamin D receptor (VDR), for […]

Apoptosis in different gastric lesions and gastriccancer: relationship with Helicobacter pylori,overexpression of p53 and aneuploidy

A.C. Targa, A.C.G. César, P.M. Cury, A.E. SilvaPublished September 30, 2007Genet. Mol. Res. 6 (3): 554-565 (2007) About the authorA.C. Targa, A.C.G. César, P.M. Cury, A.E. Silva Corresponding authorA.E. SilvaE-mail: anabete@ibilce.unesp.br ABSTRACT Apoptosis has an essential function in maintaining the integrity of the gastrointestinal mucosa. Its deregulation is associated with the occurrence of lesions such […]

Cytogenetic analysis and description of the sexual chromosome determination system ZZ/ZW of species of the fish genus Serrapinnus (Characidae, Cheirodontinae)

A.P. Santi-Rampazzo, P.B. Nishiyama, P.E.B. Ferreiraand I.C. Martins-SantosPublished August 30, 2007Genet. Mol. Res. 6 (3): 504-509 (2007) About the authorA.P. Santi-Rampazzo, P.B. Nishiyama, P.E.B. Ferreiraand I.C. Martins-Santos Corresponding author: I.C. Martins-SantosE-mail: icmdsantos@uem.br ABSTRACT Four populations of Serrapinnus notomelas and one population of Serrapinnus sp.1, both belonging to the subfamily Cheirodontinae, were analyzed by Giemsa and […]

Evaluation of genetic diversity in a naturalrosewood population (Dalbergia nigra Vell.Allemão ex Benth.) using RAPD markers

F.S. Juchum, J.B. Leal, L.M. Santos, M.P. Almeida, D. Ahnert, R.X. CorrêaPublished September 30, 2007Genet. Mol. Res. 6 (3): 543-553 (2007) About the authorF.S. Juchum, J.B. Leal, L.M. Santos, M.P. Almeida, D. Ahnert, R.X. Corrêa Corresponding author: F.S. JuchumE-mail: fsjuchum@yahoo.com.br ABSTRACT Dalbergia nigra (rosewood) is a long-lived leguminous species, which is endemic to the Brazilian […]

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