Research Article

Single Nucleotide Polymorphisms associated with growth and carcass traits located on QTL Regions previously associated with Bovine Respiratory Disease

Published: December 01, 2017
Genet. Mol. Res. 16(4): gmr16039843 DOI: 10.4238/gmr16039843


The objective of the current study was to evaluate single
nucleotide polymorphisms (SNP) for potential growth and carcass trait
associations located in two previously described quantitative trait loci
(QTL) regions associated with bovine respiratory disease. A population
of 323 crossbred steers sired by five purebred sire breeds between 2010-
2013 (Angus, Braford, Braunvieh, Charolais, and Simmental) were
evaluated from birth until harvest. Eighty-two SNP were evaluated in
the current study for potential significant associations with growth and
carcass traits (58 on BTA6 and 24 on BTA20). A total of nine unique
SNP (rs41595713, rs42403565, rs42571566, rs42900130, rs41931108,
rs42480445, rs43451134, rs42524450, rs41626155) were significantly
associated (P < 0.05) with specific growth traits such as birth weight,
weaning weight and hip height. Six of these significant SNP were
located on BTA6 and three were located on BTA20. When evaluating
the carcass traits hot carcass weight (HCW), yield grade (YG), marbling
score (MARB), and rib eye area (REA) a total of nine unique SNP
(rs42900130, rs42961882, rs43446022, rs41931108, rs41595713,
rs41653357, rs43036576, rs42823614, rs42512588) were significantly
associated (P < 0.05) with carcass traits. For both of these regions,
animals inheriting differing genotypes from the previously described
SNP, had significantly different levels of performance for specific 
growth and carcass traits. Although multiple SNP were identified as
significant with growth and carcass traits, these SNP identified herein
must be validated in a larger more diverse population prior to
implementation into marker assisted selection programs.