Mutual information content of homologous DNA sequences

Helena Cristina G. Leitão, Luciana S. Pessôa, Jorge Stolfi
Published September 30, 2005
Genet. Mol. Res. 4 (3): 553-562 (2005)

About the Authors
Helena Cristina G. Leitão, Luciana S. Pessôa, Jorge Stolfi

Corresponding author
H.C.G. Leitão
Email: hcgl@ic.uff.br

ABSTRACT

The necessary information to reproduce and keep an organism is codified in acid nucleic molecules. Deepening the knowledge about how the information is stored in these bio-sequences can lead to more efficient methods of comparing genomic sequences. In the present study, we analyzed the quantity of information contained in a DNA sequence that can be useful to identify sequences homologous to it. To reach it, we used signal processing techniques, specially spectral analysis and information theory.

Key words: DNA sequence analysis, Homologous DNA sequences, Information theory, Fourier analysis.

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