Edward de O. Ribeiro, Gustavo G. Zerlotini, Irving R.M. Lopes, Victor B.R. Ribeiro, Alba C.M. Melo, Maria Emilia M.T. Walter, Marcos Mota Costa, BIOFOCO Network
Published September 30, 2005
Genet. Mol. Res. 4 (3): 590-598 (2005)

About the Authors
Edward de O. Ribeiro, Gustavo G. Zerlotini, Irving R.M. Lopes, Victor B.R. Ribeiro, Alba C.M. Melo, Maria Emilia M.T. Walter, Marcos Mota Costa, BIOFOCO Network

Corresponding author
E.O. Ribeiro
Email: edward@cic.unb.br

ABSTRACT

Interpro is a widely used tool for protein annotation in genome sequencing projects, demanding a large amount of computation and representing a huge time-consuming step. We present a strategy to execute programs using databases Pfam, PROSITE and ProDom of Interpro in a distributed environment using a Java-based messaging system. We developed a two-layer scheduling architecture of the distributed infrastructure. Then, we made experiments and analyzed the results. Our distributed system gave much better results than Interpro Pfam, PROSITE and ProDom running in a centralized platform. This approach seems to be appropriate and promising for highly demanding computational tools used for biological applications.

Key words: Distributed systems, Interpro, Computational biology, Tools.