Lipid

Differential expression of lipid metabolism genes in the liver and adipose tissue of mice treated with evodiamine

D. F. Jiang, Zhang, X. G., Yang, H. L., and Sun, C., Differential expression of lipid metabolism genes in the liver and adipose tissue of mice treated with evodiamine, vol. 12, pp. 1501-1510, 2013.

Evodiamine is the main active alkali of Wu Zhuyu, a widely distributed Chinese herb. It plays an important role in the regulation of body fat deposition. In this study, we aimed to investigate the effect of evodiamine administration on the expression of genes involved in lipid metabolism in the liver and adipose tissue. Fasted mice were subcutaneously injected with evodiamine (37°C, 20 mg/kg), and the core body temperature change and expression levels of lipid metabolism-related genes were evaluated at baseline, 0.5, 1, and 2 h.

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