HPLC

Trans-resveratrol concentrations and antimutagenic potential of juice from the grape cultivars Vênus, BRS Violeta and Isabel

N. C. V. Polonio, Rocha, C. L. M. S. C., and Clemente, E., Trans-resveratrol concentrations and antimutagenic potential of juice from the grape cultivars Vênus, BRS Violeta and Isabel, vol. 13, pp. 1152-1159, 2014.

Grape juice, in addition to being an energetic food, due to its high sugar content, has several compounds that can prevent or treat various types of diseases. Resveratrol is a compound present in grapes that has attracted a lot of interest; in addition to preventing cardiovascular disease linked to lipid metabolism, it has chemopreventive and chemotherapeutic activities. We evaluated the antimutagenic activity and determined the trans-resveratrol content in grape juice from the varieties Vênus, BRS Violeta and Isabel.

Molecular characterization of Aspergillus flavus and aflatoxin contamination of wheat grains from Saudi Arabia

A. S. Al-Wadai, Al-Othman, M. R., Mahmoud, M. A., and El-Aziz, A. R. M. Abd, Molecular characterization of Aspergillus flavus and aflatoxin contamination of wheat grains from Saudi Arabia, vol. 12, pp. 3335-3352, 2013.

Twelve species belonging to six fungal genera were found to be associated with wheat (Triticum aestivum L.) grain samples collected from three main regions in Saudi Arabia. The most common genera (average frequency) were Aspergillus (14.3%), Fusarium (29.1%), Penicillium (9.3%), and Alternaria (8.2%). Nineteen isolates of Aspergillus flavus were screened for their ability to produce aflatoxins using HPLC. Thirteen isolates produced aflatoxins ranging from 0.5 to 2.6 μg/kg.

Hemoglobin I-Philadelphia [alpha 16 (A14) LYS→GLU] heterozygote among blood donors from Brazil

F. R. Torres, Ondei, L. S., Silva, R. U., Cavasini, C. E., Bonini-Domingos, C. R., Zamaro, P. J. A., Rossit, A. R. B., and Machado, R. L. D., Hemoglobin I-Philadelphia [alpha 16 (A14) LYS→GLU] heterozygote among blood donors from Brazil, vol. 5. pp. 713-716, 2006.

We describe a heterozygous case of Hb I-Philadelphia [alpha 16 (A14) LYS→GLU] in a blood donor from the Acre State Blood Bank, in the Brazilian Amazon region. We confirmed the mutation by electrophoretic and chromatographic methods and by DNA sequencing. A literature search showed that this is the first description of this alpha globin mutant in a Brazilian Caucasian group. We also emphasize the importance of the hemoglobin study in blood donors for the purpose of the genetic counseling and quality assurance of the blood to be transfused.

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