CD40

CD40 functional gene polymorphisms and mRNA expression in rheumatoid arthritis patients from western Mexico

I. V. Román-Fernández, Ávila-Castillo, D. F., Cerpa-Cruz, S., Gutiérrez-Ureña, S., Hernández-Bello, J., Padilla-Gutiérrez, J. R., Valle, Y., Ramírez-Dueñas, M. G., Pereira-Suárez, A. L., and Muñoz-Valle, J. F., CD40 functional gene polymorphisms and mRNA expression in rheumatoid arthritis patients from western Mexico, vol. 15, no. 4, p. -, 2016.

INTRODUCTION

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects diarthrodial joints. RA affects ∼1% of the world’s population and is characterized by synovial hyperplasia, infiltration of large numbers of inflammatory cells into the joints, production of autoantibodies, systemic inflammation, and cardiovascular complications (McInnes and Schett, 2011; Arend and Firestein, 2012).

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