EXPLORATION OF GUAVA (PSIDIUM GUAJAVA LINN.) LEAVES EXTRACT IN PHARMACEUTICAL DOSAGE FORM AND ITS EVALUATION

Abstract

Guava (Psidium guajava L.) family Myrtaceae is a small tree or shrub. This plant is native to South America and Mexico. This plant shows many biological activities such as antimicrobial, anti-inflammatory, anti-diarrheal, hepato-protective. Alcohol and ethyl acetate extract contains many phyto-constituents that was alkaloids, flavanoids, saponins, tannins, steroids, glycosides, carbohydrates, phenolic compounds. Nanogel formulation was prepared by using ethyl acetate extract of leaves, sodium alginate, sodium benzoate, propylene glycol, distilled water, triethanolamine for pH adjustment. The pH was found to be 6-7. The formulated gel was greenish in color, homogeneous, non-irritant to skin, translucent, easily spread. The concentration in formulated gel was found to be 0.79%.