COMPARISON OF TRIPLE-HERBAL THERAPY VERSUS TAMSULOSIN IN PATIENTS WITH MILD TO MODERATE BPH

Abstract

Background: A common cause of troublesome lower urinary tract symptoms in senior men is benign prostatic hyperplasia. While tamsulosin works, side effects can make it less likely to be used, and there is growing interest in standardized herbal alternatives. Objective: To evaluate the effectiveness and safety of triple-herbal therapy versus tamsulosin in patients with mild to moderate BPH. Materials and Methods: A total of 200 patients were included in this randomized controlled trial (RCT) conducted in the Department of Urology, PIMS Hospital, Islamabad, from 02-07-2026 to 24-09-2026. The participants were treated with triple-herbal therapy or tamsulosin 0.4 mg per day for 12 weeks. The outcomes measured were IPSS, Qmax, PVR, adherence, and adverse effects. Results: Both groups had significant improvement in IPSS, Qmax, and PVR in the illustrative analysis. Triple-herbal therapy had lower rates of adverse effects and marginally improved adherence compared to tamsulosin. Conclusion: Triple-herbal therapy is likely to offer symptom improvement similar to that of tamsulosin, but greater tolerability, and larger, masked, multicenter trials and longer follow-up periods are needed.