EFFECT OF STAPHYLOCOCCUS AUREUS INFECTION ON KIDNEY FUNCTIONS AND RENAL PERFORMANCE

Abstract

Background : Staphylococcus aureus is a type of Gram-positive bacteria that causes many diseases in humans, moving between the tissues and organs of the human body, including urinary tract infections and skin infections Methodology : A total of 40 samples were collected, distributed as follows: 10 samples from the control group (healthy individuals), 10 samples from patients with urinary tract infections, 10 samples from patients with Staphylococcus aureus bacteriosis, and 10 samples from patients with Staphylococcus aureus sepsis. Blood was drawn from patients and healthy individuals in all study samples.

Result: Results were different because older people, especially those with urinary catheters, were more susceptible to UTIs. Sepsis patients had higher blood urea and creatinine levels than other groups. The group with Staphylococcus aureus sepsis had significantly higher C-reactive protein, procalcitonin, white blood cell count, and LDH levels. The tests' relationships with each other and with age were likewise strongly correlated.

Aim of study: Assessing the levels of kidney disease tests like urea, creatinine, C-reactive protein, LDL enzyme, procalcitonin, and white blood cells with age and their relationship to Staphylococcus aureus bacteria, which causes urinary tract infections, bacteremia, and sepsis.

Conclusion: This study suggests that Staphylococcus aureus infections start with inflammation and progress to bacteremia. If left untreated or without antibiotics, the bacteria may release virulence factors, causing sepsis and blood poisoning. These illnesses can kill. Kidney function, white blood cell count, and C-reactive protein testing are needed to determine the body's response to the infection and the spread of the bacterial toxin. Important diagnostic information can be gained. Urine protein is another important indicator of illness progression. The stage and severity of the sickness are also determined by biological indicators such procalcitonin and LDH levels. They also help determine the antibiotics that can slow the sickness by considering the bacteria's susceptibility.