IN PATIENTS WITH BREAST CANCER, THE LEVELS OF S100 CALCIUM-BINDING PROTEIN B (S100B) AND SOME BIOCHEMICAL MARKERS ARE RELATED TO ORAL HEALTH

Abstract

The most common cancer in women is breast cancers. Therefore, even though additional indicators are needed to improve accuracy, early detection of breast cancer is beneficial for treatment. The objectives of the research were to ascertain how these markers affect breast cancer patients, how S100B levels contribute to early breast cancer diagnosis, and how these markers connect to oral health. There were a significant increase in levels of ALP and S100B in breast cancer women in comparison with pathological and healthy controls . While there were no significantly differ in levels of  S100B,when compared pathological controls to healthy controls. These S100B and ALP values can be utilized to distinguish between benign and malignant breast cancers.While a significant decrease in 1,25(OH)2 Vitamin D, phosphorus patients with breast cancer in comparison with healthy controls. These values make these parameters highly significant for early diagnosis and progression of breast cancer. Serum calcium and fibroblast growth factor 23 (FGF23) levels were shown to be significantly elevated in breast cancer and were suggested as useful disease indicators. For the development and upkeep of dental health, FGF23 and vitamin D are essential. Together with calcium, phosphorus contributes to the development of strong enamel, which is essential for preventing cavities and rotting in teeth.