SPECTROSCOPIC ANALYSIS OF DIABETIC FOOT ULCER PATIENTS

Abstract

An infected diabetic foot ulcer is the common cause of morbidity in diabetic patients leading to complications like gangrene and amputation. Illuminate, A Device that helps in the identification and type of bacteria (Gram-positive or negative) and In point of care settings by Multispectral autofluorescence imaging is considered simple, affordable, and non-time consuming and initiates appropriate antibiotics without any delay. The device excites the bacterial organisms with ultraviolet and blue light which in turn have characteristic emission of fluorescence from the organism that has been captured by the device, records the spectral signature, An Inbuilt image is processed and the artificial intelligence algorithm in the machine detects the native fluorescence emitted by the bacteria according to their Gram type. This study was done in a tertiary care hospital With a total of 15 number of Patients, where we evaluated both spectroscopy and standard culture sensitivity test and found that the illuminate device was able to detect the microorganism with 92.9% Sensitivity and 50% Specificity to the culture sensitivity test and with the accuracy of 71.15%. This device has the potential to help clinicians to identify wound with significant bacteria which maximizes the treatment for the infected diabetic foot ulcer with early start of appropriate antibiotics.