REVIEW OF ADJUVANTS IN PCOS MANAGEMENT

Abstract

Background: PCOS (polycystic ovarian syndrome) is a multisystem condition that is common and affects 8–13% of women worldwide. The main pathogenic processes behind the development and course of this condition are unknown. Although there is currently no established cure for PCOS, symptoms are managed with lifestyle changes, menstrual cycle control, androgen reduction, and metabolic improvement. Resveratrol, Quercetin, and Curcumin are believed to have therapeutic benefits for PCOS. In order to find evidence-based information about Resveratrol, Quercetin, and Curcumin for PCOS, this meta-analysis was carried out. Objective: To determine whether managing individuals who have polycystic ovary syndrome (PCOS) with resveratrol, quercetin, and curcumin improves the condition, despite the fact that the only proven treatments for PCOS are symptomatic measures like hormone medication, menstrual cycle management, lifestyle modification, androgen reduction and metabolic improvement. Methods: This investigation used the PubMed and Google Scholar databases to find original research articles. The primary information source for this study was articles published between 2016 and 2024. Results and Conclusions: A total of thirty-two studies were assessed as suitable for inclusion in the meta-analysis. Out of thirty-two research articles that were included, seventeen research articles dealt with human subjects and fifteen research articles with animal subjects. We investigated the pool of article’s means and standard deviations. Resveratrol, quercetin, and curcumin may have positive therapeutic benefits in PCOS, according to the findings of these studies. As an instance, this meta-analysis additionally offers insights into the outcomes of each specified research article.