Integrating Functional Genomics and Crispr-Based Inquiry into Undergraduate Life Science Education

Abstract

The development of genomic technologies has revolutionized both life science research and undergraduate education. The development of functional genomics, which focuses on gene functions and their interactions at the systems level, and CRISPR-Cas genome editing, which allows for precise and heritable genome editing, have become core technologies in modern biological disciplines. The paper aims to discuss the theoretical rationale for functional genomics and CRISPR-Cas genome editing technologies in undergraduate life science education. It is evident that functional genomics provides an integrated framework for understanding gene expression, gene regulation, and genotype-phenotype relationships. On the other hand, CRISPR-Cas and CRISPR-Cas-ML genome editing technologies provide an opportunity for undergraduate students to manipulate genomic DNA directly and to understand gene interactions without depending on transgenic approaches. The use of functional genomics with CRISPR-Cas genome editing technologies provides an opportunity for overcoming some of the major conceptual challenges facing undergraduate life science students. The use of these technologies at different levels of curriculum development provides an opportunity for making an impact in undergraduate life science education.