DEDIFFERENTIATED LIPOSARCOMA OF THE RIGHT AXILLA AND ONCOLOGIC MANAGEMENT WITH FOREQUARTER AMPUTATION

Abstract

Dedifferentiated liposarcoma is an aggressive soft tissue sarcoma that rarely arises in the axilla. An 84-year-old woman presented with a painless, progressively enlarging right axillary mass associated with upper limb weakness and numbness. Imaging demonstrated a large heterogeneous axillary tumor with chest wall extension, brachial plexus involvement, and axillary vessel encasement. Core biopsy suggested pleomorphic sarcoma. Due to extensive local involvement precluding limb-sparing resection, a right forequarter amputation was performed. Histopathology confirmed FNCLCC grade 3 dedifferentiated liposarcoma with positive anterior margins. The patient received adjuvant chemotherapy and remains disease-free at one-year follow-up.