ASSESSMENT OF HEPATIC FIBROSIS USING SHEAR WAVE ELASTOGRAPHY AND ITS CORRELATION WITH SEROLOGICAL FIBROSIS MARKERS IN CHRONIC LIVER DISEASE: A CROSS-SECTIONAL STUDY

Abstract

Background: The worldwide occurrence of diseases in the liver is very common. The assessment of hepatic fibrosis degree is very useful for staging and managing pathology. SMPs, TEs, and SHREs are being used by more chronic hepatitis patients to assess liver fibrosis non-invasively.

Aim: SWE's involvement in hepatic fibrosis evaluation and connection with blood indicators was examined in CLD patients.

Materials and Methods: A total of 84 adults with chronic liver disease were included in the study. Liver transient elastography was performed utilizing the Sound Touch Elastography (TEC) feature on the MINDRAY DC-80 USG system. This study used serological fibrosis indicators (apri), FIB-4, and King's Score (derived from laboratory data) as stiffness indices. Using Spearman, we correlated SWE with fibrosis markers.

Results: The average was 46.44 men and 69.05% women. Alcoholism (39.29%) and non-alcoholic fatty liver disease (NAFLD) (35.71%) caused most liver damage. The average value of liver stiffness was 11.44 ± 3.28 kPa.  42.86% of patients had cirrhosis while 33.33% experienced advanced fibrosis as per SWE. SWE utilized.

Conclusion: SWE is a trustworthy non-invasive method for evaluating fibrosis in the liver of individuals suffering from chronic liver disease.