REPRODUCTIVE HEALTH AND RENAL PHYSIOLOGY IN VETERINARY PRACTICE: EMERGING INSIGHTS

Abstract

Renal physiology and reproductive health are closely related on the metabolic, endocrine, and vascular levels; nevertheless, the clinical interaction between them is not fully defined in the field of veterinary medicine. Subclinical or early renal dysfunction can have systemic effects that can undermine reproductive performance before we can know that the disease has struck. The objective of the current study was to determine the relationship between the renal physiological status and reproductive health parameters in the veterinary patients. The study was a cross-sectional observational one that involved fifty domestic animals that were subjected to routine clinical assessment. The reproductive health was examined based on the breeding history, clinical examination, and the imaging-based assessment of the reproductive organs, whereas the renal physiological status was evaluated based on the routine biochemical indicators with the support of clinical and diagnostic results. Animals were grouped depending on their reproductive status and the level of severity of renal functions. The relationships among renal and reproductive variables were studied using descriptive and comparative analysis. Animals with mild to moderate renal dysfunction showed a greater level of subfertility and irregular reproductive behaviours than those animals which had a normal renal functioning. Normal renal condition was strongly linked to stable reproductive functioning, but progressive renal impairment was linked to gradual decrease of reproductive functioning. This result suggests that there is a clinically important relationship between renal physiological changes and reproductive outcome in veterinary patients. The research indicates the necessity of the inclusion of renal testing in regular reproductive check-ups and emphasizes on the possible usefulness of multidisciplinary diagnostic methods. Longitudinal and mechanistic studies in the future are justified to elucidate the causality and to maximize clinical interventions to enhance fertility and health of the animals.