New insights into telomeric DNA sequence (TTAGGG)n location in bat chromosomes

K.C. Faria, S.R.C. Marchesin, P.R.L. Moreira, M.R. Beguelini, E. Morielle-Versute
Published: September 01, 2009
Genet. Mol. Res. 8 (3) : 1079-1084
DOI: https://doi.org/10.4238/vol8-3gmr637

Cite this Article:
K.C. Faria, S.R.C. Marchesin, P.R.L. Moreira, M.R. Beguelini, E. Morielle-Versute (2009). New insights into telomeric DNA sequence (TTAGGG)n location in bat chromosomes. Genet. Mol. Res. 8(3): 1079-1084. https://doi.org/10.4238/vol8-3gmr637

About the Authors
K.C. Faria, S.R.C. Marchesin, P.R.L. Moreira, M.R. Beguelini, E. Morielle-Versute.

Corresponding Author
E. Morielle-Versute
E-mail: morielle@ibilce.unesp.br

ABSTRACT

Molossidae species, Cynomops abrasus (2n = 34, fun­damental number, FN = 64), Eumops auripendulus (2n = 42, FN = 62), Molossus rufus (2n = 48, FN = 64), Molossops temminckii (2n = 48, FN = 64), and Nyctinomops laticaudatus (2n = 48, FN = 64), and Phyl­lostomidae species, Phyllostomus discolor (2n = 32, FN = 60), have karyotypes with different chromosome and fundamental numbers, dif­ferent localization of constitutive heterochromatin, and different num­bers and location of nucleolar organizer regions (NORs). Fluorescence in situ hybridization with a human probe of the telomeric sequence (TTAGGG)n produced fluorescent signals in telomeric regions of the six bat species’ chromosomes; in E. auripendulus, pericentromeric signals were also observed in the acrocentric and subtelocentric chro­mosomes. A relationship between telomeric sequences and NORs, and between telomeric sequences and constitutive heterochromatin was de­tected in chromosomes bearing NORs in C. abrasus, M. temminckii, N. laticaudatus, and P. discolor. No interstitial signal was observed in the meta- or submetacentric chromosomes of these species.
Key words: Fluorescence in situ hybridization, Molossid, Phyllostomid; Chiroptera, Telomeric sequence.

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