T.D. Cam, T.H. Anh, H.T. Le, N.D.P. Kieu, T.A. Hoang
Published: March 25, 2021
Genet. Mol. Res. 20(1): GMR18729
DOI: https://doi.org/10.4238/gmr18729
Cite this Article:
T.D. Cam, T.H. Anh, H.T. Le, N.D.P. Kieu, T.A. Hoang (2021). Adherence to blood pressure control and association with comorbidities in elderly Vietnamese patients. Genet. Mol. Res. 20(1): GMR18729. https://doi.org/10.4238/gmr18729
About the Authors
T.D. Cam, T.H. Anh, H.T. Le, N.D.P. Kieu, T.A. Hoang
Corresponding Author: T.D. Cam
Email: truongcam1967@gmail.com
ABSTRACT
To date, the only study to evaluate blood pressure control in Vietnam in accordance with Eighth Joint National Committee (JNC 8) recommendations has been Nguyen Van Tri’s 2015 study, which included nearly 6,000 older people with hypertension. This study showed that the proportion of blood pressure control at that time was 21.9%. We examined the relationship between blood pressure control and functional status, associated chronic diseases, multiple diseases, and medication. This was a descriptive cross-sectional study using multivariate analysis. The subjects of the study were patients with arterial hypertension older than 60 years who underwent outpatient treatment at the clinic of the department of the senior headquarters of the 175 Military Hospital of the Ministry of Defense from October 2015 to March 2016. There were significant associations between blood pressure control and orthostatic hypotension (OR = 0.456, 0.26-0.81 95% CI, P < 0.007), daily activity (Activities of Daily Living, ADL) (OR = 0.127, 0.06-0.25 95% CI, P < 0.025), instrumental activities (Instrumental Activities of Daily Living, IADL) (OR = 0.270, 0.16-0.47, 95% CI, P < 0.007), dyslipidemia (OR = 0.534, 0.307-0.927 95% CI, P < 0.024), diabetes (OR = 0.293, 0.19-0.45 95% CI, P < 0.001), chronic kidney disease (CKD) (OR = 0.307, 0.181-0.522 95% CI, P < 0.001), cardiovascular diseases (OR = 0.389, 0.218-0.694 95% CI, P < 0.001) and multiple drug therapy (OR = 0.529, 0.332-0.844 95% CI, P < 0.007). The greatest association was with ADL/IADL, diabetes and CKD. It is imperative to increase control over blood pressure, especially for patients with such concomitant diseases as diabetes mellitus and chronic kidney disease.
Key words: Arterial hypertension, Blood pressure control, Chronic kidney disease, Diabetes, Orthostatic hypotension.