Research Article

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Animals; Body composition; Body size; Breeding; Cattle; Genome-wide association study; Genotype; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable

In arid and semi-arid zones, animal health and production are closely correlated with body conformation traits. These selected traits, in turn, allow livestock to adapt unfavorable soil and environmental conditions. The primary objective of this study was to perform a genome-wide association analysis for a set of sampled and imputed SNPs with 16 conformation traits in a population of Holstein ... more

M.E. González; V.M. González; M.F. Montaño; G.E. Medina; P. Mahadevan; C. Villa; R. Villa
4/20/2017
Adolescent; Adult; Alleles; Case-control studies; China; Female; Genotype; Humans; Interleukin-6; Keloid; male; Middle Aged; Polymorphism, Single Nucleotide

The aim of the present study is to explore the effect of IL-6 gene polymorphisms on the development of keloid scar (KS) in the Chinese Han population. Genotyping of IL-6 was performed by the polymerase chain reaction (PCR), followed by restriction fragment length polymorphism assays (PCR-RFLP). Serum level of IL-6 was measured using enzyme-linked immunosorbent assay (ELISA). Results indicated ... more

X.J. Zhu; W.Z. Li; H. Li; C.Q. Fu; J. Liu
4/20/2017
Animals; Body weight; Chickens; Genotype; Polymorphism, Restriction Fragment Length; Quantitative Trait, Heritable; Receptors, Somatomedin

Growth traits are important economic traits in broiler chicken production. AluI and Hin1I loci are two restriction sites, which are respectively located in exons 2 and 3 of the IGF-1R gene. These two loci are significantly related to the growth traits in Jinghai Yellow chickens. In this study, a correlation analysis was performed between these two loci and the growth traits of Bian chickens. ... more

P.F. Wu; D. Wang; C.F. Jin; X.Q. Zhang; H.Q. Wu; L. Zhang; F.X. Ding; K.Z. Xie; G.X. Zhang
4/28/2017
Dipteryx; Gene frequency; Genetic markers; Genotype; High-Throughput Nucleotide Sequencing; Microsatellite Repeats; Polymorphism, Genetic; Sequence Analysis, DNA

The use of next-generation sequencing (NGS) technologies provides a great volume of genome sequence data even for non-model species. The development of microsatellite markers using these data is a relatively quick and easy process. Dipteryx alata Vogel (Fabaceae) is an arboreal species from the Cerrado biome and is considered an important plant genetic resource. Here, we report the development ... more

R.A. Guimarães; M.P.C. Telles; A.M. Antunes; K.M. Corrêa; C.V.G. Ribeiro; A.S.G. Coelho; T.N. Soares
5/04/2017
Atherosclerosis; Case-control studies; Female; Genotype; Heterozygote; Humans; male; Middle Aged; Mutation, Missense; Nitric Oxide Synthase Type III; Polymorphism, Single Nucleotide

Atherosclerotic and its cardiovascular complications are responsible for 17.5 million deaths a year, according to the World Health Organization. There is consensus that atherosclerosis involves multiple pathogenic processes initiated by endothelial dysfunction, with inflammation and vascular proliferation determining alterations in the matrix, with consequent formation of the atheromatous ... more

F.L. Campedelli; K.S.F.E. Silva; D.A. Rodrigues; J.V.M. Martins; I.R. Costa; M.H. Lagares; A.M. Barbosa; M.P. de Morais; K.K.V.O. Moura
5/04/2017
Edible Grain; Genotype; Quantitative Trait, Heritable; Sorghum

Given the importance of selecting lines to obtain hybrids, we aimed to verify the relationship between morphological traits that can be used as the criteria for the selection of sorghum lines with high grain yield and earliness. A total of 18 traits were evaluated in 160 sorghum elite lines, in an incomplete block design with two replicates. A correlation network was used to graphically ... more

K.J. da Silva; P.E. Teodoro; C.B. de Menezes; M.P.M. Júlio; V.F. de Souza; M.J. da Silva; L.D. Pimentel; A. Borém
5/04/2017
Animals; Aquaculture; Gene frequency; Genotype; HSP70 Heat-Shock Proteins; Penaeidae; Polymorphism, Single Nucleotide

Single nucleotide polymorphisms (SNPs) are the best genetic markers for associative studies of the immune system in invertebrates. In the marine shrimp Litopenaeus vannamei, SNPs linked to disease resistance have been reported for some genes, such as hemocyanin, anti-lipopolysaccharide factor, and heat-shock protein 70 (Hsp70). In the present study, polymorphisms in the Hsp70 gene were ... more

A.L. Ferreira; R. Maggioni; D. Conceição; L.M. Perazzolo; R.L. Petersen
05/10/2017
Epistasis, Genetic; Eucalyptus; Genotype; Models, Genetic; Quantitative Trait, Heritable

Understanding non-additive effects in the expression of quantitative traits is very important in genotype selection, especially in species where the commercial products are clones or hybrids. The use of molecular markers has allowed the study of non-additive genetic effects on a genomic level, in addition to a better understanding of its importance in quantitative traits. Thus, the purpose of ... more

I.C. Vieira; J.P.R.Dos Santos; L.P.M. Pires; B.M. Lima; F.M.A. Gonçalves; M. Balestre
05/10/2017
Adaptation, Physiological; Droughts; Genotype; Germination; Osmotic pressure; Plant breeding; Selection, Genetic; Soybeans

Water deficit is the main reason for instability in the context of soybean culture. The development of strategies for the selection of more tolerant genotypes is necessary. These strategies include the use of polyethylene glycol 6000 solutions (PEG-6000) for conducting the germination test under conditions of water restriction. Thus, the objective of this study was to determine the osmotic ... more

S.A.G. Dantas; F.C.S. Silva; L.J. Silva; F.L. Silva
05/18/2017
Ecosystem; Genotype; Phenotype; Plant breeding; Polymorphism, Genetic; Quantitative Trait, Heritable; Selection, Genetic; Vigna

Estimating genetic parameters in plant breeding allows us to know the population potential for selecting and designing strategies that can maximize the achievement of superior genotypes. The objective of this study was to evaluate the genetic potential of a population of 20 cowpea genotypes by estimating genetic parameters and path analysis among the traits to guide the selection strategies. ... more

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