Research Article

Related GMR Articles

Flooding; Heat-shock proteins; Oryza sativa

Although flooding is one of the most important environmental stresses worldwide, not all plant species are intolerant to its effects. Species from semi-aquatic environments, such as rice, have the capacity to cope with flooding stress. Heat-shock proteins (Hsps) are thought to contribute to cellular homeostasis under both optimal and adverse growth conditions. Studies of gene expression ... more

L.M. Mertz-Henning; C. Pegoraro; L.C. Maia; E. Venske; C.V. Rombaldi; C. de Oliveira; L.M. Mertz-Henning; C. Pegoraro; L.C. Maia; E. Venske; C.V. Rombaldi; C. de Oliveira
Bcl-2; Cervical cancer; KAI1; Metastasis; Survivin

Cervical cancer is associated with abnormal expression of multiple genes. Survivin and Bcl-2 proteins are apoptosis inhibitors. The tumor suppressor gene CD82, which encodes the protein KAI1, is downregulated in cervical cancer, and is associated with differentiation degree. We investigated the expression levels of three proteins and their correlation with metastasis in cervical ... more

X.L. Zhou; M. Wang
Papillary thyroid carcinoma; Pathogenesis; Signaling pathway; Survivin

The purpose of this study was to assess the correlation between the survivin gene and the occurrence and pathogenesis of papillary thyroid carcinoma (PTC). Sixty patients with PTC and no preoperative chemotherapy were recruited for the study and 30 thyrophyma patients receiving operative treatment in Drum Tower Hospital (Nanjing, China) were included as the control group. The protein ... more

J.Y. Li; J. Shi; J.F. Sang; Y.Z. Yao; X.C. Wang; L. Su
Livin; Nanoparticle; PC-3M; Prostate cancer; RNA interference; Survivin

Monomethoxypolyethylene glycol-chitosan (mPEG-CS) nanoparticles were used as interfering RNA carriers to transfect human prostate cancer PC-3M cells to evaluate the effects of livin and survivin gene silencing on the proliferation and apoptosis. mPEG-CS nanoparticles with sizes of approximately 60 nm were first synthesized by ionic crosslinking. Through electrostatic adsorption, mPEG-CS- ... more

A.Q. Yang; P.J. Wang; T. Huang; W.L. Zhou; J. Landman; A.Q. Yang; P.J. Wang; T. Huang; W.L. Zhou; J. Landman; A.Q. Yang; P.J. Wang; T. Huang; W.L. Zhou; J. Landman
Apoptosis; Caspase 3; Lipid-associated membrane proteins; Mycoplasma hyopneumoniae

Lipid-associated membrane proteins (LAMPs) are important in the pathogenicity of the Mycoplasma genus of bacteria. We investigated whether Mycoplasma hyopneumoniae LAMPs have pathogenic potential by inducing apoptosis in a St. Jude porcine lung epithelial cell line (SJPL). LAMPs from a pathogenic strain of M. hyopneumoniae (strain 232) were used in the research. Our ... more

B. Ni; F.F. Bai; Y. Wei; M.J. Liu; Z.X. Feng; Q.Y. Xiong; L.Z. Hua; G.Q. Shao
Apoptosis; Liver cirrhosis; Macrophage; Renal injury; Xiayuxue decoction

Renal pathological changes in cirrhotic rat have not been extensively reported. The aim of this study was to investigate whether Xiayuxue decoction (XYXD) could attenuate renal injury induced by bile duct ligation (BDL), with special focus on the mechanisms promoting renal macrophage apoptosis. The rats were treated with BDL for 5 weeks and administered 0.36 g/kg XYXD intragastrically from day ... more

C. Liu; J. Cai; Z. Cheng; X. Dai; L. Tao; J. Zhang; D. Xue
A431 cells; Apoptosis; Bcl-2; Berberine; Proliferation; Squamous cell carcinoma

Berberine (BBR) is a natural alkaloid with significant anti-tumor activity against many types of cancer cells. In this study, we investigated the molecular mechanisms employed by BBR to repress the proliferation and growth of skin squamous cell carcinoma A431 cells. Berberine was reported to inhibit the proliferation of A431 cells in a dose- and time-dependent manner and was observed to induce ... more

D.X. Li; J. Zhang; Y. Zhang; P.W. Zhao; L.M. Yang
Acute cerebral infarction; Apoptosis; Baculovirus P35 protein

We explored the effect of baculovirus P35 protein on apoptosis in the brain tissue of rats with acute cerebral infarction (ACI). A rat model of middle cerebral artery infarction was created. The rats were randomly divided into sham, model, and treatment groups. Baculovirus P35 protein was injected into the intracranial arteries of the treatment group rats. The rats in the model group were ... more

J.F. Ji; X.H. Ma
5-aminolevulinic acid; Apoptosis; Sonodynamic therapy; UMR-106 cells

We investigated the killing effect of low-intensity ultrasound combined with 5-aminolevulinic acid (5-ALA) on the rat osteosarcoma cell line UMR-106. Logarithmic-phase UMR-106 cells were divided into a control group, ultrasound group and 5-ALA group. The cell apoptotic rate, production of reactive oxygen species, and the change in mitochondrial membrane potential were analyzed by flow ... more

Y.N. Li; Q. Zhou; B. Yang; Z. Hu; J.H. Wang; Q.S. Li; W.W. Cao
Apoptosis; cFLIP; Corpus albicans; Corpus luteum; Porcine

We determined expression and localization of the anti-apoptotic cellular FLICE inhibitory protein (cFLIP) in the porcine corpora lutea (CL) and corpus albicans (CA) during estrous and preg­nancy. The CL and CA were collected at different stages of estrous to determine cFLIP immunolocalization, and mRNA and protein ex­pression. The mRNA expression of the short cFLIP isoform (cFLIPS ... more

H.Z. Jin; W.S. Shi; Y. Tian; Y. Liu; Y. Jin; N. Manabe