Research Article

Related GMR Articles

2017 Mar 22
Animals; Biomarkers; Chickens; China; Female; Genome-wide association study; Haplotypes; Linkage disequilibrium; male; Polymorphism, Single Nucleotide; Quantitative trait loci; Quantitative Trait, Heritable; Reproduction; Selective breeding

Reproductive traits have long been studied and have an important influence on chicken breeding. To identify quantitative trait loci affecting reproductive traits, a genome-wide analysis of a Chinese chicken breed was performed to analyze age at first egg body weight at first egg, first egg weight, egg weight at the age of 300 days, egg weight at the age of 462 days, egg number at the age of ... more

Q.C. Fan; P.F. Wu; G.J. Dai; G.X. Zhang; T. Zhang; Q. Xue; H.Q. Shi; J.Y. Wang
2016 Dec 02
Animals; Body weight; Cattle; Genome-wide association study; Genotype; Models, Biological; Phenotype; Polymorphism, Single Nucleotide; Quantitative trait loci

This study aimed to investigate the predictability of a phenotype when using a dynamic model of cattle growth. Genotypic and phenotypic information on Nellore (Bos indicus) cattle were used in a genome-wide association analysis designed to contrast the biological interpretation of core parameters [conversion efficiency of metabolizable energy to net energy for gain (k) and adjusted final ... more

M.C. Freua; M.H.A. Santana; R.V. Ventura; J.B.S. Ferraz
2017 Jul 06
Animals; Bayes Theorem; Body weight; Cattle; Female; male; maternal inheritance; Quantitative Trait, Heritable; Selective breeding

This study was carried out to investigate (co)variance components and genetic parameters for growth traits in beef cattle using a multi-trait model by Bayesian methods. Genetic and residual (co)variances and parameters were estimated for weights at standard ages of 120 (W120), 210 (W210), 365 (W365), and 450 days (W450), and for pre- and post-weaning daily weight gain (preWWG and postWWG) in ... more

F.B. Lopes; J.L. Ferreira; R.B. Lobo; G.J.M. Rosa
2016 Dec 02
Animals; Avian Proteins; Chickens; Female; Genetic association studies; Genotype; Insulin-like growth factor I; Phenotype; Polymorphism, Single-Stranded Conformational; Quantitative trait loci; Reproduction; Selection, Genetic

The insulin-like growth factor, IGF-I, plays an important role in the development of growth and reproductive traits. Single-strand conformation polymorphism analysis was used to detect and analyze polymorphisms and expression profiles of the IGF-I gene and its association with growth and reproductive traits of Jinghai yellow chickens. A point mutation g.295T>C was detected in the IGF-I gene ... more

M.A. Abdalhag; T. Li; L. Duan; T. Zhang; G. Zhang; J. Wang; Y. Wang
2017 Apr 13
Animals; Body composition; Body size; Breeding; Cattle; Genome-wide association study; Genotype; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable

In arid and semi-arid zones, animal health and production are closely correlated with body conformation traits. These selected traits, in turn, allow livestock to adapt unfavorable soil and environmental conditions. The primary objective of this study was to perform a genome-wide association analysis for a set of sampled and imputed SNPs with 16 conformation traits in a population of Holstein ... more

M.E. González; V.M. González; M.F. Montaño; G.E. Medina; P. Mahadevan; C. Villa; R. Villa
2017 Mar 22
Actins; Animal Feed; Animals; Cattle; Chemokine CCL5; Diet; Female; Interleukin-8; Lactalbumin; Lactation; Mammary Glands, Animal; Milk; Milk proteins; Random Allocation; Rumen

In order to evaluate the milk yield, milk quality, and health of dairy cows fed a high-concentrate (HC) diet, eight lactating Holstein dairy cattle were randomly assigned to HC or low-concentrate (LC) diet groups and fed for 50 days, and the auto-control studying before and after treatment with the two diets was used. During the experiment, plasma and milk samples were collected and measured. ... more

Z.L. Xie; J. Zhang; D.M. Zhang; J.F. Li; Y.H. Lin
2016 Dec 19
Animals; Cattle; Embryo Culture Techniques; Female; Gene Expression Regulation, Developmental; GRB10 Adaptor Protein; Point mutation; Polymorphism, Single Nucleotide; Quantitative trait loci; Sequence Analysis, DNA; Superovulation

The application of assisted reproductive technology in animal production benefits the economy and conservation of biological resources. Single nucleotide polymorphism (SNPs) was used as predictive markers for breeding and reproduction. In the present study, we examined the association between a SNP of the grb10 gene and superovulation traits in cattle. Sequencing results indicated a point ... more

Y. Wu; Z. Zhang; J.B. Zhang; Q. Deng
2017 Feb 16
Animals; Calcium-Binding Proteins; Calpain; Cattle; Gene frequency; Genetic markers; Genotype; Polymorphism, Single Nucleotide; Quantitative trait loci; Red Meat

The objectives of this study were to characterize the allelic and genotypic frequencies of polymorphisms in the µ-calpain and calpastatin genes, and to assess their association with meat tenderness and animal growth in Nellore cattle. We evaluated 605 Nellore animals at 24 months of age, on average, at slaughter. The polymorphisms were determined for the molecular markers CAPN316, CAPN530, ... more

M.E. Carvalho; J.P. Eler; M.N. Bonin; F.M. Rezende; F.H. Biase; F.V. Meirelles; L.C.A. Regitano; L.L. Coutinho; J.C.C. Balieiro; J.B.S. Ferraz
2017 Apr 13
Animals; Animals, Inbred Strains; Ear; Extracellular Matrix Proteins; Gene expression profiling; Genome-wide association study; Intercellular Signaling Peptides and Proteins; Methionine Sulfoxide Reductases; Quantitative trait loci; RNA, Messenger; Swine

Porcine ear size is an important characteristic for distinguishing among pig breeds. In a previous genome-wide association study of porcine ear size, LEM domain-containing 3 (LEMD3), methionine sulfoxide reductase B3 (MSRB3), high mobility group AT-hook 2 (HMGA2), and Wnt inhibitory factor 1 (WIF1) were implicated as important candidate genes for ear size. This study investigated the ... more

L.C. Zhang; J. Liang; L. Pu; Y.B. Zhang; L.G. Wang; X. Liu; H. Yan; L.X. Wang
2017 Jun 29
Animals; Bacterial Proteins; Cattle; Drug Resistance, Microbial; Female; Genotype; Mastitis, Bovine; Milk; Phenotype; Polymorphism, Genetic; Staphylococcus aureus

The Staphylococcus aureus is the most common isolated microorganism in ruminant animal species diagnostic with clinical or subclinical mastitis. Dairy herds with these diseases can transfer S. aureus into the milk supply, which can lead to food poisoning in humans. The objective of this study was to evaluate the profile of antimicrobial susceptibility, the presence of femA gene, the genetic ... more

A.R.E.O. Xavier; A.C. Almeida; C.N. Souza; L.M.V. Silva; A.X.A. Ruas; D.A. Sanglard; A.F.M. Júnior; A.M.E. Oliveira; M.A.S. Xavier

Pages