Research Article

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5/04/2017

Hsp70 gene polymorphisms in farmed marine shrimp Litopenaeus vannamei populations exposed to white spot disease and infectious myonecrosis.

Animals; Aquaculture; Gene frequency; Genotype; HSP70 Heat-Shock Proteins; Penaeidae; Polymorphism, Single Nucleotide

Single nucleotide polymorphisms (SNPs) are the best genetic markers for associative studies of the immune system in invertebrates. In the marine shrimp Litopenaeus vannamei, SNPs linked to disease resistance have been reported for some genes, such as hemocyanin, anti-lipopolysaccharide factor, and heat-shock protein 70 (Hsp70). In the present study, polymorphisms in the Hsp70 gene were ... more

A.L. Ferreira; R. Maggioni; D. Conceição; L.M. Perazzolo; R.L. Petersen
05/18/2017

Genotyping of SNPs associated with meat tenderness: comparison of two PCR-based methods.

Animals; Calcium-Binding Proteins; Calpain; Cattle; Genotyping Techniques; Leptin; meat; Polymerase chain reaction; Polymorphism, Single Nucleotide

Single nucleotide polymorphisms (SNPs) carried in calpain (CAPN1), calpastatin (CAST), and leptin (LEP) genes are associated with meat tenderness. Due to the economic importance of this meat quality attribute, the development of fast, reliable, and affordable methods to identify bovine carriers of favorable alleles is of great importance for genetic improvement. Currently, PCR-RFLP is accepted ... more

L.E. López-Rojas; L. Patiño-Cadavid; A. López-Herrera; J.J. Echeverri-Zuluaga
05/25/2017

Effects of cell death-inducing DFF45-like effector B on meat quality traits in Berkshire pigs.

Animals; Apoptosis Regulatory Proteins; meat; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable; RNA, Messenger; Swine

Cell death-inducing DFF45-like effector (CIDE) B is a member of the CIDE family of apoptosis-inducing factors. In the present study, we detected a single nucleotide polymorphism (SNP), c.414G>A, which corresponds to the synonymous SNP 414Arg, in CIDE-B in the Berkshire pigs. We also analyzed the relationships between the CIDE-B SNP and various meat quality traits. The SNP was significantly ... more

G.E. Yu; S. Kwon; J.H. Hwang; S.M. An; D.H. Park; D.G. Kang; T.W. Kim; I.S. Kim; H.C. Park; J. Ha; C.W. Kim
09/21/2017

Study of genetic variability in pigs after the traditional breeding program.

Animals; Diacylglycerol O-Acyltransferase; Genotype; Growth hormone; Leptin; Polymorphism, Single Nucleotide; Receptors, Leptin; Selective breeding; Swine

Molecular markers are tools used to improve genetic gains. The objective of this study was to analyze the security of alleles of molecular marker genes for characteristics of economic interest in a pure population of pigs. After the extraction of DNA from the hair of 272 Large White matrices, the allele and genotype frequency of single nucleotide polymorphism was performed using the ARMS-PCR ... more

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Effects of mutant TDP-43 on the Nrf2/ARE pathway and protein expression of MafK and JDP2 in NSC-34 cells.

Amyotrophic lateral sclerosis; Animals; Cell line; DNA-Binding Proteins; MafK Transcription Factor; Mice; Mutation, Missense; NAD(P)H Dehydrogenase (Quinone); Neurons; NF-E2-Related Factor 2; Oxidative stress; Repressor Proteins; Response Elements

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects motor neurons and lacks an effective treatment. The disease pathogenesis has not been clarified at present. Pathological transactive response DNA-binding protein 43 (TDP-43) plays an important role in the pathogenesis of ALS. Nuclear translocation of nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) is ... more

Y.P. Tian; F.Y. Che; Q.P. Su; Y.C. Lu; C.P. You; L.M. Huang; S.G. Wang; L. Wang; J.X. Yu

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