Research Article

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2017 Aug 31
Arecaceae; Evolution, Molecular; Gene flow; Gene frequency; Heterozygote; Linkage disequilibrium; Microsatellite Repeats; Polymorphism, Genetic

We assessed the level and distribution of genetic diversity in three species of the economically important palm genus Astrocaryum located in Pará State, in northern Brazil. Samples were collected in three municipalities for Astrocaryum aculeatum: Belterra, Santarém, and Terra Santa; and in two municipalities for both A. murumuru: Belém and Santo Antônio do Tauá and A. paramaca: Belém and ... more

N.P. Oliveira; M.S.P. Oliveira; L.C. Davide; S. Kalisz
2017 Sep 27
Ecuador; Gene frequency; Humans; Microsatellite Repeats; Polymorphism, Genetic; Population

One hundred and eighty-two samples of unrelated people who requested the paternity test at the Molecular Biology and Genetics Laboratory of the Catholic University of Cuenca-Ecuador in the province of Azuay were studied, except for the D1S1656 (180 samples) and SE33 (89 samples) markers. The STRs D22S1045, D3S1358, VWA, D16S539, D2S1338, D8S1179, D21S11, D18S51, D19S433, TH01, FGA, D1S1656, ... more

P.P. Orellana; C.F. Andrade; C.L. Arciniegas; G.C. Iannacone
2016 Dec 02
Adult; Alanine; Arginine; Asian Continental Ancestry Group; Diabetes Mellitus, Type 2; Female; Genetic predisposition to disease; Genotype; Glutamine; Humans; Leucine; male; Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Superoxide dismutase; Threonine

The most common type of endocrine disease is type 2 diabetes mellitus (T2DM); genetic factors contribute to the development to T2DM. In this study, we investigated the role of the Leu53Leu, Arg213Gly, and Ala40Thr polymorphisms in extracellular superoxide dismutase (EC-SOD) gene in the development of T2DM in a Chinese population. DNA was extracted from peripheral blood samples obtained from ... more

Y.M. Yang; X.R. Xie; A.L. Jin
2016 Dec 02
Animals; Avian Proteins; Chickens; Female; Genetic association studies; Genotype; Insulin-like growth factor I; Phenotype; Polymorphism, Single-Stranded Conformational; Quantitative trait loci; Reproduction; Selection, Genetic

The insulin-like growth factor, IGF-I, plays an important role in the development of growth and reproductive traits. Single-strand conformation polymorphism analysis was used to detect and analyze polymorphisms and expression profiles of the IGF-I gene and its association with growth and reproductive traits of Jinghai yellow chickens. A point mutation g.295T>C was detected in the IGF-I gene ... more

M.A. Abdalhag; T. Li; L. Duan; T. Zhang; G. Zhang; J. Wang; Y. Wang
2016 Dec 19
Adult; Aromatase; Asian Continental Ancestry Group; Case-control studies; Endometriosis; Female; Genetic predisposition to disease; Genotype; Glutathione S-Transferase pi; Glutathione transferase; Humans; Polymorphism, Single Nucleotide; Young Adult

Endometriosis is a common, complicated, and highly heterogeneous endocrine disease. Many genetic factors could affect the development of endometriosis. We performed a case-control study to evaluate the association between polymorphisms in CYP19A1 rs2899470, GSTM1, GSTT1, and GSTP1 rs1695 and the development of endometriosis in a Chinese population. Between March 2014 and October 2015, 262 ... more

Y. Tuo; J.Y. He; W.J. Yan; J. Yang
2016 Dec 23
Alleles; Case-control studies; Female; Genetic predisposition to disease; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polycystic ovary syndrome; Polymorphism, Single Nucleotide

Polycystic ovary syndrome is one of the most frequently encountered endocrine malfunctions. Methylenetetrahydrofolate reductase (MTHFR) plays a vital role in folate metabolism, DNA methylation, and RNA synthesis. We carried out a study to investigate the association between MTHFR C677T and A1298C genetic variations and the risk of polycystic ovary syndrome in a Chinese population. We recruited ... more

J.B. Wu; J.F. Zhai; J. Yang
2017 Jan 23
Alleles; Colorectal neoplasms; Genetic association studies; Genetic predisposition to disease; Genotype; Humans; Mexico; Odds Ratio; Polymorphism, Single Nucleotide; PPAR delta

PPARD encodes for peroxisome proliferator-activated receptor delta, which plays a significant role in controlling lipid metabolism, atherosclerosis, inflammation, cancer growth, progression, and apoptosis. Accumulated evidence suggests that the polymorphism rs2016520 in PPARD is associated with lipid metabolism, obesity, metabolic syndrome, and type 2 diabetes mellitus. The aim of this study ... more

M.A. Rosales-Reynoso; L.I. Wence-Chavez; A.R. Arredondo-Valdez; S. Dumois-Petersen; P. Barros-Núñez; M.P. Gallegos-Arreola; S.E. Flores-Martínez; J. Sánchez-Corona
2017 Mar 22
Animals; Crosses, Genetic; Disease resistance; Genotype; Hemiptera; Lycopersicon esculentum; Pest Control, Biological; Pheromones; Plant breeding; Plant Diseases; Tetranychidae

The mini tomato production has expanded, becoming an amazing alternative for enterprise. Despite all commercial potential, the cultivation has the occurrence of pests as main obstacle during the crop development. Nowadays, there are no researches that aimed obtaining genotypes with high acylsugar content, capable of providing a broad-spectrum resistance to pests. This study aimed the selection ... more

G.M. Maciel; R.S. Almeida; J.P.R. da Rocha; V. Andaló; G.R. Marquez; N.C. Santos; R.R. Finzi
2017 Mar 16
Animals; Disease resistance; Genotype; Host-Parasite Interactions; Multivariate analysis; Phaseolus; Plant Diseases; Plant Roots; Random Allocation; seeds; Tylenchoidea

The availability of common bean cultivars tolerant to Meloidogyne javanica is limited in Brazil. Thus, the present study aimed to evaluate the reactions of 33 common bean genotypes (23 landrace, 8 commercial, 1 susceptible standard and 1 resistant standard) to M. javanica, employing multivariate statistics to discriminate the reaction of the genotypes. The experiment was conducted in a ... more

L.N.S. Santos; P.D.S. Cabral; G.A.R. Neves; F.R. Alves; M.B. Teixeira; F.N. Cunha; N.F. Silva
2017 Mar 16
Animals; Base Sequence; Conserved sequence; Disease resistance; Evolution, Molecular; Genetic markers; Genetic variation; Genotype; Microsatellite Repeats; Phylogeny; Plant Diseases; Plant Proteins; Psidium; Tylenchoidea

Guava (Psidium guajava L.) crop is severely affected by the nematode Meloidogyne enterolobii. Native Psidium species have been reported as sources of resistance against this nematode. Knowledge on the molecular relationship between Psidium species based on plant resistance gene analogs (RGA) can be useful in the genetic breeding of guava for resistance to M. enterolobii. In this study, RGA ... more

L.R. Noia; A.C. Tuler; A. Ferreira; M.F.S. Ferreira