Research Article

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Body weight; Brazilian sheep; Genetic gain; Heritability

Studying genetic parameters and genetic changes in Santa Ines sheep is important, because it is the commonest breed in Brazil. This study obtained genetic data from 37,735 pedigree records of lambs over 12 years (2003-2014) from 33 flocks in 10 Brazilian States; 11,851 records of performance were available. (Co)variance components, genetic parameters and breeding values estimates were ... more

E.L. Aguirre; E.C. Mattos; J.P. Eler; A.D.Barreto Neto; J.B. Ferraz; E.L. Aguirre; E.C. Mattos; J.P. Eler; A.D.Barreto Neto; J.B. Ferraz
avTOR; Chickens; Feed efficiency; Gene expression

Avian target of rapamycin (avTOR) is a highly conserved serine-threonine kinase that serves as an intracellular energy and nutrient sensor and regulates cell division, growth, and apoptosis. The role of avTOR in mediating feed intake and growth in poultry is unknown. We studied avTOR signaling activities in duodenum and liver tissues at days 35 and 42 in chickens divergently selected for ... more

J. Lee; S.E. Aggrey; J. Lee; S.E. Aggrey
Bone tumor; CYP1A1; Genetic susceptibility; Genotype; GSTM1

Tumor gene polymorphisms are often associated with individual susceptibility to genetic diseases. Cytochrome P4501A1 (CYP1A1) and glutathione S-transferase mu 1 (GSTM1) gene polymorphisms are closely related to the susceptibility of the body to chemical carcinogens in the environment. Therefore, we explored the relationship between CYP1A1 and GSTM1 gene ... more

L. Li; J.G. Li; C.Y. Liu; Y.J. Ding
Genotype; Hepatitis B virus; Sequence analysis

Hepatitis B virus genotype C (HBV/C) has the largest number of subgenotypes (C1-C16) that vary with geography and isolates. HBV/C prevails in Southeast Asia (C1, C5-C16), East Asia (C2), Oceania (C3), and Australia (C4). Suitable reference strains for different subgenotypes could greatly facilitate research into HBV/C, but unfortunately they are scarce. We retrieved 974 HBV/C full-length ... more

H.L. Zhu; C.T. Wang; J.B. Xia; X. Li; Z.H. Zhang
Genotype; Goat; Milk protein; Polymorphism; SDS-PAGE

This study evaluates the relationship between the genotype and milk protein components in goats. Milk samples were collected from cloned goats and normal white goats during different postpartum (or abortion) phases. Two cloned goats, originated from the same somatic line of goat mammary gland epithelial cells, and three sexually reproduced normal white goats with no genetic relationships ... more

H. Xing; B. Shao; Y.Y. Gu; Y.G. Yuan; T. Zhang; J. Zang; Y. Cheng
Cervical intraepithelial neoplasia; Cervical squamous cell carcinoma; Chronic cervicitis; Genotype; HPV

This study aimed to investigate human papilloma virus (HPV) genotypes among women with cervical lesions in Shaanxi Province, China, to obtain information regarding cervical lesion prevention and treatment. The study included 4508 HPV-positive subjects; cervical swab specimens were collected and tested for HPV infection status and HPV genotypes using polymerase chain reaction and reverse ... more

J. Li; Y.Y. Wang; X. Nan; X.F. Tian; T. Yan; P. Wang; Y. Yin; Y. Liu; R. Yuan; G.Q. Wang; Y.L. Fu; J. Li; Y.Y. Wang; X. Nan; X.F. Tian; T. Yan; P. Wang; Y. Yin; Y. Liu; R. Yuan; G.Q. Wang; Y.L. Fu; J. Li; Y.Y. Wang; X. Nan; X.F. Tian; T. Yan; P. Wang; Y. Yin; Y. Liu; R. Yuan; G.Q. Wang; Y.L. Fu
2016 Dec 02
Adult; Alanine; Arginine; Asian Continental Ancestry Group; Diabetes Mellitus, Type 2; Female; Genetic predisposition to disease; Genotype; Glutamine; Humans; Leucine; male; Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Superoxide dismutase; Threonine

The most common type of endocrine disease is type 2 diabetes mellitus (T2DM); genetic factors contribute to the development to T2DM. In this study, we investigated the role of the Leu53Leu, Arg213Gly, and Ala40Thr polymorphisms in extracellular superoxide dismutase (EC-SOD) gene in the development of T2DM in a Chinese population. DNA was extracted from peripheral blood samples obtained from ... more

Y.M. Yang; X.R. Xie; A.L. Jin
2016 Dec 02
Crosses, Genetic; Genotype; Phenotype; Quantitative trait loci; Zea mays

The successful development of hybrid cultivars depends on the reliability of estimated combining ability of the parent lines. The objectives of this study were to assess the combining ability of partially inbred S families of popcorn derived from the open-pollinated variety UENF 14, via top-crosses with four testers, and to compare the testers for their ability to discriminate the S progenies ... more

V.J. de Lima; A.T. do Amara Junior; S.H. Kamphorst; G.F. Pena; J.T. Leite; K.F.M. Schmitt; C. Vittorazzi; J.E. de Almei Filho; F. Mora
2016 Dec 19
China; Chromosomes, Plant; Cotton Fiber; Genotype; Gossypium; Plant breeding; Polymorphism, Genetic; Quantitative trait loci

Upland cotton (Gossypium hirsutum L.) is an important cash crop that provides renewable natural fiber worldwide. Currently limited genetic base leads to a decrease in upland cotton genetic diversity. Multi-parent advance generation inter-cross (MAGIC) populations can be used to evaluate complex agronomic traits in crops. In this study, we developed an upland cotton MAGIC population. A total of ... more

D.G. Li; Z.X. Li; J.S. Hu; Z.X. Lin; X.F. Li
2016 Dec 19
Adult; Aromatase; Asian Continental Ancestry Group; Case-control studies; Endometriosis; Female; Genetic predisposition to disease; Genotype; Glutathione S-Transferase pi; Glutathione transferase; Humans; Polymorphism, Single Nucleotide; Young Adult

Endometriosis is a common, complicated, and highly heterogeneous endocrine disease. Many genetic factors could affect the development of endometriosis. We performed a case-control study to evaluate the association between polymorphisms in CYP19A1 rs2899470, GSTM1, GSTT1, and GSTP1 rs1695 and the development of endometriosis in a Chinese population. Between March 2014 and October 2015, 262 ... more

Y. Tuo; J.Y. He; W.J. Yan; J. Yang