Research Article

Related GMR Articles

4/28/2017
Biomarkers, Tumor; Carcinoma, Signet Ring Cell; CDX2 Transcription Factor; Codon; Female; Genes, ras; Humans; male; Middle Aged; Mucins; Mutation; Mutation Rate; Neoplasm Metastasis; Phenotype; Stomach neoplasms

We aimed to analyze gastric signet ring cell (SRC) carcinoma subtypes by investigating gastric and intestinal phenotypic marker expression, and explore the relationship between phenotype and K-ras mutation. Immunohistochemistry was performed on 163 SRC carcinoma patient specimens to detect gastric (MUC1, MUC5AC, and MUC6) and intestinal (MUC2 and CDX2) phenotypic markers, and tumors were ... more

Z.F. Xiong; J. Shi; Z.H. Fu; H.P. Wan; L.X. Tu
09/27/2017
Genome, Plant; Iron; Oryza; Phenotype; Plant Proteins; Stress, Physiological; Transcription factors

Iron (Fe) is an essential microelement for all living organisms playing important roles in several metabolic reactions. Rice (Oryza sativa L.) is commonly cultivated in paddy fields, where Fe goes through a reduction reaction from Fe to Fe. Since Fe is more soluble, it can reach toxic levels inside plant cells, constituting an important target for studies. Here we aimed to verify morphological ... more

V.E. Viana; N. Marini; T. Finatto; I. Ezquer; C. Busanello; R.S.Dos Santos; C. Pegoraro; L. Colombo; C. de Oliveira
12/19/2016
Animals; Animals, Genetically Modified; Apoptosis Regulatory Proteins; Crosses, Genetic; Drosophila melanogaster; Drosophila Proteins; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Humans; male; Membrane Proteins; Neurons; Proto-Oncogene Proteins c-bcl-2; Sequence Homology, Amino Acid; Transgenes

Lifeguard is an integral transmembrane protein that modulates FasL-mediated apoptosis by interfering with the activation of caspase 8. It is evolutionarily conserved, with homologues present in plants, nematodes, zebra fish, frog, chicken, mouse, monkey, and human. The Lifeguard homologue in Drosophila, CG3814, contains the Bax inhibitor-1 family motif of unknown function. Downregulation of ... more

P.G. M'Angale; B.E. Staveley
1/23/2017
Breeding; Crosses, Genetic; Disease resistance; Genes, Plant; Genetic markers; Microsatellite Repeats; Oryza; Plant Diseases

Rice (Oryza sativa L.) blast disease is one of the most destructive rice diseases in the world. The fungal pathogen, Magnaporthe oryzae, is the causal agent of rice blast disease. Development of resistant cultivars is the most preferred method to achieve sustainable rice production. However, the effectiveness of resistant cultivars is hindered by the genetic plasticity of the pathogen genome. ... more

N. Hasan; M.Y. Rafii; A. Rahim; S.A. Nusaibah; N. Mazlan; S. Abdullah
2/08/2017
Crosses, Genetic; Hybridization, Genetic; Manihot

Two cassava escapes where collected from cultivated fields near natural habitat in Bolivia. They are described morphologically and analyzed cytogenetically in this study. It is suggested that they are the product of backcrosses of cassava interspecific hybrids with the cultigen itself, and that selective conditions have developed in which certain forms of cassava segregates have adapted to ... more

N.M.A. Nassar; M. Mendonza
06/20/2017
Breeding; Crosses, Genetic; Quantitative Trait, Heritable; Zea mays

The REML/BLUP statistics are analyses that can be used as selective criteria in the routine of maize breeding programs. The present study aims to determine the genetic potential in crosses of landrace populations applying the REML/BLUP methodology, and to identify populations for the synthesis of new populations and intrapopulation selection for family farming systems, as well as genetic ... more

D. Baretta; M. Nardino; I.R. Carvalho; A.J. de Pelegrin; M. Ferrari; V.J. Szareski; W.S. Barros; V.Q. de Souza; A.C. de Oliveira; L.C. da Maia
05/18/2017
Jatropha; Microsatellite Repeats; Polymorphism, Genetic

Physic nut (Jatropha curcas L.) presents high oilseed yield and low production cost. However, technical-scientific knowledge on this crop is still limited. This study aimed to evaluate and estimate the genetic variability of hybrids obtained from dialell crossing. Genetic variability was carried out using ISSR molecular markers. For genetic variability, nine primers were used, and six were ... more

D.O. Ribeiro; R. Silva-Mann; S.V. Alvares-Carvalho; E.M.S. Souza; M.C. Vasconcelos; A.F. Blank
3/16/2017
Animals; Anti-Inflammatory Agents; Brazil; Carrageenan; Cell Movement; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Leukocytes; male; Mangifera; Medicine, Traditional; Mice; Oils, Volatile; Peroxidase; Plant Leaves; Plant Oils; Rats

Mangifera indica is widely found in Brazil, and its leaves are used as an anti-inflammatory agent in folk medicine. The aim of this study is to perform composition analysis of essential oils from the M. indica varieties, espada (EOMIL1) and coração de boi (EOMIL2), and confirm their anti-inflammatory properties. Twenty-three volatile compounds were identified via gas chromatography-mass ... more

R.M. Oliveira; T.S. Dutra; E. Simionatto; N. Ré; C.A.L. Kassuya; C.A.L. Cardoso
3/16/2017
Antifungal Agents; Ascomycota; Fusarium; Gas Chromatography-Mass Spectrometry; Microbial Sensitivity Tests; Mitosporic Fungi; Ocimum; Oils, Volatile; Plant Leaves; Plant Oils; Rhizoctonia

Ocimum gratissimum L. or clove basil, belongs to the Lamiaceae family, has various desirable uses and applications. Beyond its aromatic, seasoning, and medicinal applications, this plant also has antimicrobial activity. This study was aimed at assessing the antifungal activity, yield, and composition of the essential oil (EO) of O. gratissimum. The species was cultivated in garden beds with ... more

F.B.M. Mohr; C. Lermen; Z.C. Gazim; J.E. Gonçalves; O. Alberton
08/17/2017
Cells, Cultured; DNA damage; Euterpe; Fruit; Hep G2 Cells; Humans; Lymphocytes; Plant Oils

Euterpe oleracea Mart., popularly known as "açaí", is a tropical fruit from the Amazon region where it has considerable economic importance. Açaí has been used as food and for several medicinal purposes. Despite the widespread use of this fruit, there is a lack of data regarding the safety of using this fruit oil exclusively. Therefore, we evaluated the in vitro cytotoxic, genotoxic, and ... more

E.S. Marques; M.S.F. Tsuboy; J.C.T. Carvalho; P.C.P. Rosa; F.F. Perazzo; I.O.M. Gaivão; E.L. Maistro

Pages