Research Article

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05/18/2017
Animals; Calcium-Binding Proteins; Calpain; Cattle; Genotyping Techniques; Leptin; meat; Polymerase chain reaction; Polymorphism, Single Nucleotide

Single nucleotide polymorphisms (SNPs) carried in calpain (CAPN1), calpastatin (CAST), and leptin (LEP) genes are associated with meat tenderness. Due to the economic importance of this meat quality attribute, the development of fast, reliable, and affordable methods to identify bovine carriers of favorable alleles is of great importance for genetic improvement. Currently, PCR-RFLP is accepted ... more

L.E. López-Rojas; L. Patiño-Cadavid; A. López-Herrera; J.J. Echeverri-Zuluaga
12/02/2016
Animal Shells; Animals; Bivalvia; Breeding; Evolution, Molecular; Female; Fresh Water; Genetic variation; Genetics, Population; male; Microsatellite Repeats; Phenotype; Phylogeny; Quantitative trait loci

Four Hyriopsis cumingii populations, a breeding population (BP), a cultured population (FP), two wild populations from Poyang Lake (PY) and Dongting Lake (DT), and an H. schlegelii population were collected (JX), and the first filial generations (F1) were bred synchronously. The shell nacre polymorphisms, population genetic diversity, and genetic structures of the F1 of each population were ... more

L.M. Wu; Z.Y. Bai; X.J. Liu; C. Jin; H. Yin; J.L. Li
12/02/2016
Animals; Avian Proteins; Body weight; Breeding; Chickens; Female; Gene expression; Gene Expression Regulation; male; Muscle development; Myostatin; Organ Specificity; Phenotype; Quantitative trait loci

Myostatin (MSTN) is expressed in the myotome and developing skeletal muscles, and acts to regulate the number of muscle fibers. Wuding chicken large body, developed muscle, high disease resistance, and tender, delicious meat, and are not selected for fast growth. Broiler chickens (Avian broiler) are selected for fast growth and have a large body size and high muscle mass. Here, 240 one-day-old ... more

L.X. Liu; T.F. Dou; Q.H. Li; H. Rong; H.Q. Tong; Z.Q. Xu; Y. Huang; D.H. Gu; X.B. Chen; C.R. Ge; J.J. Jia
12/02/2016
Animals; Apoptosis; Cells, Cultured; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Gonadotropins, Equine; Horses; In Vitro Oocyte Maturation Techniques; Oocytes; Receptors, FSH; Receptors, LH; Receptors, LHRH; Sheep

We assessed the effects of equine chorionic gonadotropin (eCG) on oocyte in vitro maturation (IVM), apoptosis, and follicle-stimulating hormone receptor (FSHR), luteinizing hormone receptor (LHR), and gonadotropin-releasing hormone receptor (GnRHR) expression and mRNA levels. Cumulus-oocyte complexes (COCs) were recovered from sheep ovaries and pooled in groups, before being cultured in IVM ... more

S.C. Wei; Z.D. Gong; H.W. Zhao; H.Q. Liang; L.J. Lai; Y.Y. Deng
12/02/2016
Animals; Avian Proteins; Chickens; Female; Genetic association studies; Genotype; Insulin-like growth factor I; Phenotype; Polymorphism, Single-Stranded Conformational; Quantitative trait loci; Reproduction; Selection, Genetic

The insulin-like growth factor, IGF-I, plays an important role in the development of growth and reproductive traits. Single-strand conformation polymorphism analysis was used to detect and analyze polymorphisms and expression profiles of the IGF-I gene and its association with growth and reproductive traits of Jinghai yellow chickens. A point mutation g.295T>C was detected in the IGF-I gene ... more

M.A. Abdalhag; T. Li; L. Duan; T. Zhang; G. Zhang; J. Wang; Y. Wang
12/19/2016
Animals; Cell Line, Tumor; Cell Movement; Cell proliferation; Endoglin; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Thyroid Neoplasms

Thyroid cancer is the most common type of endocrine tumor. MicroRNAs (miRNAs) play a critical role in a variety of diseases, especially cancer occurrence and progression. However, the specific mechanism by which miRNAs trigger disease states has not been fully elucidated. This study aims to investigate the role of miR-27a in thyroid cancer cells. A wound healing assay was adopted to examine ... more

Y.L. Wang; W.G. Gong; Q.L. Yuan
12/19/2016
Animals; Female; Forkhead Box Protein L2; Forkhead Transcription Factors; Gene expression; Goats; Hair follicle; Quantitative trait loci; Real-time polymerase chain reaction; Toll-Like Receptors; Wnt4 Protein

The mechanism of dominant follicle selection is unclear because of its physiological complexity. However, some studies have reported that the immune system plays an important role in reproductive physiology. The objective of the current study was to investigate the differential expression of Toll-like receptors (TLRs) in the dominant (DFs) and nondominant follicles (NFs), and to determine the ... more

G.X. E; Y.J. Zhao; Y.H. Ma; M.X. Chu; Q.H. Hong; S.J. Lv; L. Zhu; F.K. Li; Y.G. Han; X. Wu; Y.F. Huang
1/23/2017
Adipose tissue; Animals; Cell differentiation; Cell proliferation; Estradiol; Female; Pregnancy; Progesterone; Rats; Stem cells

Stem cell therapy faces many problems including poor survival rates and low viability. Enhancing the biological functions of stem cells improves efficacy of therapies. Estrogen, whose levels are elevated during pregnancy, affects the properties of bone marrow mesenchymal stem cells. Evidence suggests that adipose-derived stem cells (ADSCs), which are a type of adult mesenchymal stem cells, can ... more

J.N. Li; Y. Zhang; Y.F. Wang; J.Y. Chen
1/23/2017
Animals; Biomarkers; Drugs, Chinese Herbal; Endometrium; Estrous cycle; Female; Flavonoids; Immunohistochemistry; Rats

This study aimed to investigate the effect of icariin (ICA) on thin endometrium in a rat model. To this end, 6- to 8-week-old female Sprague Dawley rats (105) were randomly divided into 7 groups: untreated, vehicle-treated (lavage with NaCl), high-dose ICA (lavage with ICA at 200 mg∙kg∙day), medium-dose ICA (lavage ICA at 100 mg∙kg∙day), low-dose ICA (lavage with ICA at 50 mg∙kg∙day), sham ... more

A.W. Le; Z.H. Wang; X.Y. Dai; T.H. Xiao; R. Zhuo; B.Z. Zhang; Z.L. Xiao; X.J. Fang
2/08/2017
Animals; DNA damage; DNA Fragmentation; Female; Ferric Compounds; Humans; Lipid peroxidation; Lymphocytes; Metal Nanoparticles; Oxidative stress; Rats; Reactive oxygen species; Silicon Dioxide

At present, the use of nanoparticles is a controversial topic, especially when analyzing their effects in human tissues. Nanoparticles (NPs) can cause oxidative stress by increasing membrane lipids peroxidation and reactive oxygen species, and decreasing intracellular glutathione. Oxidative stress plays an important role in cell signaling and inflammatory responses. It can result in ... more

J. Jiménez-Villarreal; D.I. Rivas-Armendáriz; R.D.Arellano Pérez-Vertti; O. Calderón; R. García-Garza; N.D. Betancourt-Martínez; L.B. Serrano-Gallardo; J. Morán-Martínez

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