Research Article

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01/24/2014
Adult; Emergence agitation; Isoflurane; Propofol

Distal radius fracture is a common wound. It is reduced by surgery under anesthesia. Emergence agitation can often occur after anesthesia. It is associated with increased morbidity and hospital costs. However, there have been almost no reports in the medical literature on the occurrence of emergence agitation in adults. This study aimed to compare emergence agitation between isoflurane ... more

G.Y. Liu; Z.Q. Chen; Z.W. Zhang
10/24/2013
Chronic obstructive pulmonary disease; Meta-analysis; Polymorphism; Tumor necrosis factor-alpha

Chronic obstructive pulmonary disease (COPD) is a chronic systemic inflammatory disease; increasing evidence indicates that the TNF-α polymorphism is associated with progression of this disease. Few studies have focused upon association between TNF-α -238G/A or -863C/A polymorphism and COPD risk. Reported associations have been controversial because of small sample size and varied study ... more

K. Cui; X.Y. Ge; H.L. Ma
05/18/2015
Chronic obstructive pulmonary disease; Meta-analysis; Polymorphism; Tumor necrosis factor-alpha

The association between the TNF-α +489 G/A polymorphism and chronic obstructive pulmonary disease (COPD) remains controversial because of small group size and varied design among different studies. In the present study, a meta-analysis was conducted to assess the association between the +489 G/A polymorphism and COPD risk. A comprehensive search was conducted to identify ... more

K. Cui; X.Y. Ge; H.L. Ma
04/17/2015
Chinese indigenous goat; Immunological diversity; Major histocompatibility complex class III; Tumor necrosis factor-alpha

Tumor necrosis factor-α is a cytokine with a wide range of effects on both lymphoid and non-lymphoid cells. In this study, we identified polymorphisms in major histocompatibility complex class III gene in the 4th exon and the 3' untranslated region of tumor necrosis factor-α to evaluate the immunogenetic diversity of Chinese south indigenous goat. Three single-nucleotide polymorphisms ... more

G.X. E; R.S. Na; Y.J. Zhao; Y.H. Ma; Y.F. Huang
04/28/2016
Esophageal cancer; Genetic variant; Polymorphism; Tumor necrosis factor-alpha
H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu; H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu; H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu; H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu; H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu
08/29/2016
Acute myocardial infarction; Meta-analysis; Myocardial infarction; Polymorphism; Tumor necrosis factor-alpha

The tumor necrosis factor-alpha (TNF-α) G-308A polymorphism has been suggested to be a susceptibility factor for myocardial infarction (MI). However, differing results from various studies have led to controversial conclusions. Hence, we performed a meta-analysis to evaluate the association between TNF-α G-308A polymorphism and MI. Reported studies published before March 30, 2015 were ... more

X.P. Hua; J. Qian; C.B. Cao; J. Xie; X.T. Zeng; Z.J. Zhang; X.P. Hua; J. Qian; C.B. Cao; J. Xie; X.T. Zeng; Z.J. Zhang
10/02/2015
APC; Coronary heart disease; male; rs383830

APC is a tumor suppressor gene that is involved in the processes of cell migration and adhesion, transcriptional activation, and apoptosis. The goal of this study was to evaluate the contribution of the APC rs383830 polymorphism to coronary heart disease (CHD) in Han Chinese. A total of 783 patients with CHD and 737 controls were tested in the current association study. Although ... more

J.Y. Zhong; X.W. Zheng; H.D. Ye; H.B. Cui; W.P. Du; Z.X. Zhang; X.H. Fei; S.Y. Lin; J. Wang; J. Su; X.M. Chen; S.W. Duan
03/11/2016
male; Mutation; Polymerase chain reaction; Steroid-resistant nephrotic syndrome; WT1

Mutations in the Wilms’ tumor gene, WT1, can lead to syndromic steroid-resistant nephrotic syndrome and isolated steroid-resistant nephrotic syndrome. WT1 mutations have been identified in the majority of children with Denys-Drash or Frasier syndrome. WT1 mutations have not previously been identified in boys with sporadic isolated steroid-resistant nephrotic ... more

Y. Yang; F. Zhao; X. Tu; Z. Yu; Y. Yang; F. Zhao; X. Tu; Z. Yu
09/09/2015
Cytotherapy; Gene therapy; Hepatocyte growth factor; Mesenchymal stem cells; Pulmonary silicosis

Pulmonary silicosis is an irreversible and untreatable disease that is characterized by interstitial lesions and perpetual fibrosis in the lungs. This study was performed to determine whether mesenchymal stem cells (MSCs) and hepatocyte growth factor (HGF) could exhibit therapeutic effects on human silicosis. This non-randomized uncontrolled trial comprised four patients with pulmonary ... more

W.W. Liu; H.X. Wang; W. Yu; X.Y. Bi; J.Y. Chen; L.Z. Chen; L. Ding; D.M. Han; Z.K. Guo; Y.X. Lei
07/13/2015
Bone morphogenetic protein 9; Cell differentiation; Mesenchymal stem cells; Mitogen activated protein kinase; Signal transduction pathway

We investigated the synergistic effect of bone morphoge­netic protein 9 (BMP9) and transforming growth factor (TGF)-b in the transformation of mesenchymal stem cells into osteoblasts. We evalu­ated the effect of BMP9 and TGF-b on the induction of osteoblast for­mation. Mitogen-activated protein kinase (MAPK) pathway-related pro­teins such as p38, extracellular receptor kinase 1/2, and c- ... more

X.L. Li; Y.B. Liu; E.G. Ma; W.X. Shen; H. Li; Y.N. Zhang

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