Research Article

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E.V. Zambiazzi; A.T. Bruzi; S.R. Guilherme; D.R. Pereira; J.G. Lima; A.M. Zuffo; F.O. Ribeiro; A.E.S. Mendes; S.H.M. Godinho; M.L.M. Carvalho
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Arachis; Genotype; Plant Leaves; Plant Proteins; Resveratrol; RNA, Messenger; Stilbenes; Tetraploidy; Transcriptional activation; Ultraviolet Rays

Resveratrol is an antioxidant that is a promising antitumoral, cardioprotective and neuroprotective agent. It has been found in a restricted number of plants including peanut (Arachis hypogaea L.) and its wild relatives. The objective of this study was to understand the relationship between resveratrol content and the expression of putative resveratrol synthase genes in four Arachis genotypes ... more

P.A.S.V. Carvalho; A.C. Brasileiro; S. Leal-Bertioli; D.J. Bertioli; J.P. Silva; T.S. Agostini-Costa; M.A. Gimenes
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Elephant grass is a perennial tropical grass with great potential for energy generation from biomass. The objective of this study was to estimate the genetic diversity among elephant grass accessions based on morpho-agronomic and biomass quality traits and to identify promising genotypes for obtaining hybrids with high energetic biomass production capacity. The experiment was installed at ... more

D.A. Rossi; R.F. Daher; T.C. Barbé; R.S.N. Lima; A.F. Costa; L.P. Ribeiro; P.E. Teodoro; L.L. Bhering
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Alleles; Ascomycota; Basidiomycota; Disease resistance; Genotype; Hybridization, Genetic; Plant breeding; Plant Diseases; Selective breeding; Vigna

This study aimed at identifying and selecting through partial diallel analysis, segregating populations of cowpea resistant to Macrophomina phaseolina and Thanatephorus cucumeris, based on the evaluation of general (GCA) and specific combining ability (SCA), involved in the genetic control of resistance. For this reason, 19 grouped cowpea genotypes, considering the resistance to these ... more

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Chronic heart failure; Genotype; Glu298Asp; NOS3 gene; Polymorphism

The eNOS Glu298Asp (rs1799983) polymorphism of the NOS3 gene has been implicated as a risk factor for cardiovascular diseases; however, not all studies find significant associations. We examined this possibility in a Russian (Siberian) population. One hundred patients with chronic heart failure and 40 controls were investigated. PCR analysis was performed ... more

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Endometriosis is a chronic disease with adverse implications for fertility. We investigated the G894T polymorphism in the endothelial nitric oxide synthase gene in fertile and infertile women with endometriosis. This prospective study included a group of 52 women with a laparoscopic diagnosis of endometriosis. DNA was extracted from blood obtained from 47 patients ... more

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Chinese population; Familial aggregation; Gene polymorphism; Liver cancer; Risk factors; Transforming growth factor-β1

The goal of present study was to investigate the relationship between polymorphisms of TGF-β1 and familial aggregation of liver cancer in Guangxi Zhuang, Han, and Yao populations. We conducted a population-based case-control family study of liver cancer in Guanxi, China. A total of 214 individuals from 37 case families were surveyed for polymorphisms in TGF ... more

P.Q. Wan; J.Z. Wu; L.Y. Huang; J.L. Wu; Y.H. Wei; Q.Y. Ning
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Genetic polymorphism; Hypertension; MTHFR; Risk factors

The association of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and essential hypertension has been reported but with controversial results in diverse populations in Asia and Europe, thereby suggesting a dependency on ethnicity. The aim of this study was to investigate the association between the MTHFR C677T polymorphism and essential ... more

S.M. Ghogomu; N.E. Ngolle; R.N. Mouliom; B.F. Asa; S.M. Ghogomu; N.E. Ngolle; R.N. Mouliom; B.F. Asa; S.M. Ghogomu; N.E. Ngolle; R.N. Mouliom; B.F. Asa
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Epigenetics; High-resolution melting; Imprinted genes; Methylation; Polymerase chain reaction

High-resolution melting (HRM) is considered an inexpensive, rapid, and attractive methodology for methylation analysis. In the application of the polymerase chain reaction (PCR) to methylation analysis, amplification efficiencies are biased towards unmethylated, rather than methylated, templates: a phenomenon known as PCR bias. To overcome PCR bias, primers that include CpG site(s) and ... more

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