Research Article

Related GMR Articles

Animals; Gene frequency; Heterozygote; Humans; Polymorphism, Genetic; Software

The gene diversity or expected heterozygosity (H) is based on the allele frequency and is often used as a measure of genetic variability of populations. Knowing the pattern of spatial distribution of H can be useful for determining strategies of conservation and sampling of collections of individuals. In addition, it can allow one to detect genetic boundaries in a landscape. We adapted a ... more

A.R. da Silva; G. Malafaia; I.P.P. Menezes
Aged; Case-control studies; China; Endothelin-1; Female; Gene frequency; Humans; Hypertension; male; Middle Aged; Mutation, Missense; Polymorphism, Single Nucleotide

Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor and is involved in several vascular disorders such as hypertension. Its strong interaction with other vasoactive hormone systems suggests that the ET-1 gene (EDN1) is a potential candidate molecule that influences the risk of developing hypertension. Recently, two single nucleotide polymorphisms in EDN1 have been reported to be ... more

Z. Fang; M. Li; Z. Ma; G. Tu
Animals; Diacylglycerol O-Acyltransferase; Genotype; Growth hormone; Leptin; Polymorphism, Single Nucleotide; Receptors, Leptin; Selective breeding; Swine

Molecular markers are tools used to improve genetic gains. The objective of this study was to analyze the security of alleles of molecular marker genes for characteristics of economic interest in a pure population of pigs. After the extraction of DNA from the hair of 272 Large White matrices, the allele and genotype frequency of single nucleotide polymorphism was performed using the ARMS-PCR ... more

I.M. Ferreira; G.S. Vieira; T.F. Braga; T.C.F. Silva; M.M. Franco; R.C. Antunes
Brazil; cluster analysis; DNA Primers; DNA, Plant; Genetic markers; Genetic variation; Genotype; Morinda; Phylogeny; Plants, Medicinal; Random Amplified Polymorphic DNA Technique; Species Specificity

Morinda citrifolia L., commonly known as noni, has been used for the treatment of various diseases for over two centuries. It was introduced and widely disseminated in Brazil because of its high market value and ease of adaptation to the soil and climatic conditions of the country. The aim of this study was to estimate the genetic variability of noni accessions from the collection of Embrapa ... more

P.N. Bordallo; A.M.R. Monteiro; J.A. Sousa; F.A.S. Aragão
Alleles; Brazil; Fruit; Genetic markers; Genetic variation; Microsatellite Repeats; Myrtaceae; Phylogeny; Plant breeding; Polymorphism, Genetic; Trees; Vitamin A

Myrciaria dubia (camu-camu) is an Amazon tree that produces a tart fruit with high vitamin C content. It is probably the fruit with the highest vitamin C content among all Brazilian fruit crops and it can be used to supplement daily vitamin C dose. This property has attracted the attention of consumers and, consequently, encouraged fruit farmers to produce it. In order to identify and select ... more

C.F. Nunes; T.A. Setotaw; M. Pasqual; E.A. Chagas; E.G. Santos; D.N. Santos; C.G.B. Lima; G.M.A. Cançado
Alleles; Animals; Brazil; Breeding; Chromosome Mapping; DNA; Genetic Drift; Genetic variation; Genetics, Population; Genotype; Goats; Heterozygote; Microsatellite Repeats

The aim of this study was to access the genetic diversity and relatedness between Canindé and British Alpine goat breeds in the States of Piauí and Ceará using microsatellite markers. Genomic DNA was isolated from hair samples of 99 goats belonging to six different flocks. A panel of polymorphic heterologous microsatellite loci was used to genotype individuals. The microsatellite markers ... more

T.S. Câmara; J.F. Nunes; F.M. Diniz; G.R. Silva; A.M. Araújo
Breeding; Crosses, Genetic; Disease resistance; Genes, Plant; Genetic markers; Microsatellite Repeats; Oryza; Plant Diseases

Rice (Oryza sativa L.) blast disease is one of the most destructive rice diseases in the world. The fungal pathogen, Magnaporthe oryzae, is the causal agent of rice blast disease. Development of resistant cultivars is the most preferred method to achieve sustainable rice production. However, the effectiveness of resistant cultivars is hindered by the genetic plasticity of the pathogen genome. ... more

N. Hasan; M.Y. Rafii; A. Rahim; S.A. Nusaibah; N. Mazlan; S. Abdullah
Animals; Body weight; Cattle; Genome-wide association study; Genotype; Models, Biological; Phenotype; Polymorphism, Single Nucleotide; Quantitative trait loci

This study aimed to investigate the predictability of a phenotype when using a dynamic model of cattle growth. Genotypic and phenotypic information on Nellore (Bos indicus) cattle were used in a genome-wide association analysis designed to contrast the biological interpretation of core parameters [conversion efficiency of metabolizable energy to net energy for gain (k) and adjusted final ... more

M.C. Freua; M.H.A. Santana; R.V. Ventura; J.B.S. Ferraz
Animals; Base Sequence; Cattle; Female; Fertility; Genome; male; Polymorphism, Single Nucleotide; Pregnancy; Puberty; RNA; Selection, Genetic; Sequence Analysis, RNA; Sexual Maturation

Fertility traits, such as heifer pregnancy, are economically important in cattle production systems, and are therefore, used in genetic selection programs. The aim of this study was to identify single nucleotide polymorphisms (SNPs) using RNA-sequencing (RNA-Seq) data from ovary, uterus, endometrium, pituitary gland, hypothalamus, liver, longissimus dorsi muscle, and adipose tissue in 62 ... more

M.M. Dias; A. Cánovas; C. Mantilla-Rojas; D.G. Riley; P. Luna-Nevarez; S.J. Coleman; S.E. Speidel; R.M. Enns; A. Islas-Trejo; J.F. Medrano; S.S. Moore; M.R.S. Fortes; L.T. Nguyen; B. Venus; I.S.D.P. Diaz; F.R.P. Souza; L.F.S. Fonseca; F. Baldi; L.G. Albuquerque; M.G. Thomas; H.N. Oliveira
Brassica rapa; Chromosome Mapping; Crosses, Genetic; DNA, Plant; Frameshift mutation; Genetic markers; Haploidy; Phenotype; Sequence Analysis, DNA; Transcription factors; Trichomes

Trichomes are derived from the epidermis and constitute an ideal system for studying cell division in plants. Here, a Chinese cabbage doubled haploid (DH) line (FT) without trichomes was crossed with another DH line (PurDH-1) with trichomes to develop an F population for fine mapping of trichome control genes. Genetic analysis showed that the trichome phenotype was controlled by a single ... more

X.L. Ye; F.Y. Hu; J. Ren; S.N. Huang; W.J. Liu; H. Feng; Z.Y. Liu