Research Article

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11/03/2016
Chinese Han population; Dopamine D2 receptor; Heroin dependence; Single nucleotide polymorphism

Heroin dependence is a chronic relapsing brain disease. Researchers have reported that the dopamine D2 receptor (DRD2) is involved in the development of opiate dependence. To identify markers that contribute to the genetic susceptibility to heroin addiction, we examined the potential association between heroin dependence and ... more

N. Wang; J.B. Zhang; J. Zhao; X.T. Cai; Y.S. Zhu; S.B. Li; N. Wang; J.B. Zhang; J. Zhao; X.T. Cai; Y.S. Zhu; S.B. Li
11/03/2016
COL9A1; Congenital talipes equinovarus; Polymorphism

Talipes equinovarus is a common congenital deformity. COL9A1 polymorphisms are associated with the development of articular cartilage-related diseases. In the current study, we evaluated the relationship between COL9A1 rs1135056, rs35470562, and rs592121 genetic polymorphisms and risk of congenital talipes equinovarus ... more

X.L. Zhao; Y.J. Wang; Y.L. Wu; W.H. Han
11/03/2016
Correlation analysis; CYP1A1, GSTP1, ERCC2, XRCC1, XRCC3; Gene polymorphism; Lung cancer

Lung cancer is a common malignant tumor that is characterized by high morbidity and poor prognosis. Studies suggest that an individual’s genetic background affects the risk of developing lung cancer. Therefore, we investigated the relationship between gene polymorphisms and susceptibility to lung cancer. We recruited 308 primary lung ... more

H.X. Liu; J. Li; B.G. Ye; H.X. Liu; J. Li; B.G. Ye
11/03/2016
Asthma; Environmental factors; IL-4; Pets; Smoking

Asthma is an allergic disease characterized by hyperresponsiveness and chronic inflammation of the airway. The interleukin-4 (IL-4) gene and its single nucleotide polymorphisms are associated with asthma susceptibility in children. A case-control study was performed to evaluate the relationship between asthma risk and the ... more

L. Li; Y. Li; X.C. Zeng; J. Li; X.Y. Du
11/03/2016
Idiopathic infertility; p53 polymorphism; Spermatogenesis

Many environmental agents affect the development of male germ cells at different stages. Apoptosis is common during normal spermatogenesis; it plays an important role in controlling the number of germ cells and the disposal of defective stem cells to produce functional sperm. The presence of p53 in primary spermatocytes suggests that it ... more

M.P. de Morais; R.F. Curado; K.S.Fe Silva; K.K.V.O. Moura; J.T. Arruda
11/03/2016
Alpha-actinin 3; Angiotensin-converting enzyme; Muscle fiber; Polymorphism; Scoliosis

The etiology of adolescent idiopathic scoliosis remains unknown. Angiotensin-converting enzyme and α-actinin-3 polymorphisms influence the characteristics of muscle fibers. The aim of this study was to examine the association between idiopathic scoliosis and genetic polymorphism of angiotensin-converting enzyme and α-actinin-3. Ninety-seven females with scoliosis, ... more

R.P. Luciano; M. Wajchenberg; S.S. Almeida; C.E.N. Amorim; L.M.R. Rodrigues; R.C. Araujo; E.B. Puertas; F. Faloppa; R.P. Luciano; M. Wajchenberg; S.S. Almeida; C.E.N. Amorim; L.M.R. Rodrigues; R.C. Araujo; E.B. Puertas; F. Faloppa
11/03/2016
Berkshire pig; HSD17B4; Meat-quality trait; Single nucleotide polymorphisms

Single nucleotide polymorphisms (SNPs) are useful genetic markers that allow correlation of genetic sequences with phenotypic traits. It is shown here that HSD17B4, a bifunctional enzyme mediating dehydrogenation and anhydration during β-oxidation of long-chain fatty acids, contains a non-synonymous SNP (nsSNP) of chr2:128,825,976A>G, ... more

J.L. Jo; J.H. Hwang; S.G. Kwon; D.H. Park; T.W. Kim; D.G. Kang; G.E. Yu; I.S. Kim; J.G. Ha; C.W. Kim; J.L. Jo; J.H. Hwang; S.G. Kwon; D.H. Park; T.W. Kim; D.G. Kang; G.E. Yu; I.S. Kim; J. Ha; C.W. Kim
11/21/2016
IL-8; Meta-analysis; Periodontitis; Polymorphism

The -251A/T polymorphism in the anti-inflammatory cytokine interleukin-8 (IL-8) gene has been implicated in susceptibility to periodontitis; however, this correlation has not been elucidated. In this meta-analysis, we investigated the association between the IL-8 -251A/T polymorphism and the risk of periodontitis. All eligible case-control studies ... more

Z.J. Yang; X.P. Tang; Q.G. Lai; J.B. Ci; K.F. Yuan; Z.J. Yang; X.P. Tang; Q.G. Lai; J.B. Ci; K.F. Yuan; Z.J. Yang; X.P. Tang; Q.G. Lai; J.B. Ci; K.F. Yuan
11/21/2016
Loci transferability; Microsatellite loci; Next-generation sequencing; Sillago japonica; Sillago sihama

Sillago sihama (Forsskål, 1775), a commercially important marine fishery species in the Indo-West Pacific, is being developed as a target species for aquaculture and stock enhancement in China. However, due to the limitations of traditional isolation methods, the available microsatellite loci, or simple sequence repeats (SSRs), of S. sihama lack ... more

R.X. Wu; H.R. Zhang; S.F. Niu; Y. Zhai; X.F. Liu; R.X. Wu; H.R. Zhang; S.F. Niu; Y. Zhai; X.F. Liu

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