Research Article

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NR5A2 has been implicated in processes as diverse as steroidogenesis, cellular proliferation, ovarian follicular development, ovulation, and fertility in mammals. However, data about the relationship between NR5A2 and prolificacy in mammals are lacking. In the present study, we identified and characterized NR5A2 of Hu sheep, and investigated the correlation ... more

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Gene expression; Hu sheep; Muscle fiber development; MyHCs; YAP1

RT-PCR was used to study the temporal and spatial pattern of Yes-associated protein 1 (YAP1) and myosin heavy chain (MyHC) expression in four different skeletal muscles (i.e., longissimus dorsi muscle, soleus muscle, gastrocnemius muscle, and extensor digitorum longus) and three growth stages (i.e., 2 days old, 2 and 6 months old) of Hu Sheep. The results showed that ... more

W. Gao; W. Sun; R. Su; X.Y. Lv; Q.Z. Wang; D. Li; H.H. Musa; L. Chen; H. Zhou; H.S. Xu; W.H. Hua; W. Gao; W. Sun; R. Su; X.Y. Lv; Q.Z. Wang; D. Li; H.H. Musa; L. Chen; H. Zhou; H.S. Xu; W.H. Hua; W. Gao; W. Sun; R. Su; X.Y. Lv; Q.Z. Wang; D. Li; H.H. Musa; L. Chen; H. Zhou; H.S. Xu; W.H. Hua
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The mRNA expression levels of key genes (Smads, MSTN, and MyoG) in the TGF-β/Smad signaling pathway in Hu sheep at different growth stages (2 days, 2 months, and 6 months of age) and in different skeletal muscles (longissimus dorsi muscle and soleus muscle) and different genders were detected; and correlation of the Smad family (Smad2 ... more

Q.Z. Wang; R. Su; X.Y. Lv; W. Gao; L. Chen; J.J. Bao; J.R. Yu; L.H. Wang; W. Sun; Q.Z. Wang; R. Su; X.Y. Lv; W. Gao; L. Chen; J.J. Bao; J.R. Yu; L.H. Wang; W. Sun
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Gene expression; Hu sheep; MSTN; Smads; YAP1

The temporal and spatial patterns of Smad and Yes-associated protein 1 (YAP1) expression were investigated in skeletal muscle (gastrocnemius muscle and extensor digitorum longus) at different growth stages (2 days old, 2 and 6 months old) in Hu sheep. Smads were differentially expressed in sheep skeletal muscle, with high expression in the gastrocnemius muscle ... more

W. Gao; R. Su; W. Sun; Q.Z. Wang; X.Y. Lv; J.J. Bao; J.R. Yu; L.H. Wang; H.H. Musa; L. Chen; W. Gao; R. Su; W. Sun; Q.Z. Wang; X.Y. Lv; J.J. Bao; J.R. Yu; L.H. Wang; H.H. Musa; L. Chen
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The mechanism of dominant follicle selection is unclear because of its physiological complexity. However, some studies have reported that the immune system plays an important role in reproductive physiology. The objective of the current study was to investigate the differential expression of Toll-like receptors (TLRs) in the dominant (DFs) and nondominant follicles (NFs), and to determine the ... more

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