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Related GMR Articles

05/23/2016
ERCC2 rs13181; Glioma; Polymorphism

We conducted a case-control study to investigate the role of ERCC2 rs13181 polymorphism in glioma development. A total of 165 patients who were histopathologically diagnosed to have gliomas and 330 controls were collected at Jiujiang First People’s Hospital between July 2012 and June 2014. The ERCC2 rs13181 polymorphism was analyzed using a polymerase chain reaction - ... more

X. Gao; Y.J. Tang; G.F. Zhang; L. Yu; S.T. Qi; X. Gao; Y.J. Tang; G.F. Zhang; L. Yu; S.T. Qi
04/26/2016
Gastric cancer; miR-204; Prognosis; Serum

Deregulation of microRNAs (miRNAs) is implicated in the initiation and progression of gastric cancer (GC). Previous studies have demonstrated that miR-204 was downregulated in GC tissues. However, its expression profile in serum samples and its potential for clinical value remain unknown. Real-time PCR was performed to evaluate the expression level of serum miR-204 in patients with GC. ... more

X. Chen; X.S. Liu; H.Y. Liu; Y.Y. Lu; Y. Li; X. Chen; X.S. Liu; H.Y. Liu; Y.Y. Lu; Y. Li; X. Chen; X.S. Liu; H.Y. Liu; Y.Y. Lu; Y. Li
04/07/2016
Apoptosis; Autophagy; Beclin-1; Colorectal cancer; MicroRNA-30a; Prognosis

We investigated the associations between Beclin-1 and microRNA-30a (miR-30a) expression and the severity and treatment response in colorectal cancer (CRC). Our sample size consisted of 139 CRC patients who were treated with surgery alone. Immunohistochemistry was used to investigate the expression and prognostic significance of Beclin-1 in CRC, while the weak expression of Beclin-1 in ... more

L. Liu; T. Meng; Q.S. Wang; H.Z. Jin; Z.Q. Sun; B. Jin; F. Fang; H.J. Wang; L. Liu; T. Meng; Q.S. Wang; H.Z. Jin; Z.Q. Sun; B. Jin; F. Fang; H.J. Wang; L. Liu; T. Meng; Q.S. Wang; H.Z. Jin; Z.Q. Sun; B. Jin; F. Fang; H.J. Wang
04/04/2016
Apoptosis; Colorectal cancer; Invasion; MiR-874; Prognosis; Proliferation
X.J. Wang; M. Xia; W.P. Bi; X.J. Wang; M. Xia; W.P. Bi; X.J. Wang; M. Xia; W.P. Bi; X.J. Wang; M. Xia; W.P. Bi
05/23/2016
Colorectal cancer; Invasion; miR-452; Prognosis; Proliferation
T. Tang; G.C. Zhang; C.F. Li; Y.F. Liu; W.Y. Wang; T. Tang; G.C. Zhang; C.F. Li; Y.F. Liu; W.Y. Wang; T. Tang; G.C. Zhang; C.F. Li; Y.F. Liu; W.Y. Wang
05/12/2016
Breast cancer; Keap1; Prognosis

Our objective was to explore the expression and clinical significance of Kelch-like epichlorohydrin-associated protein 1 (Keap1) in breast cancer tissue. Eighty-one breast cancer patients having undergone surgical treatment in our hospital between March 2002 and December 2008 were enrolled in this study. Normal tissue adjacent to tumors was used for the control samples. Diagnoses for all ... more

L. Zhang; W.P. Yang; L.Y. Wu; X. Zhu; C.Y. Wei; L. Zhang; W.P. Yang; L.Y. Wu; X. Zhu; C.Y. Wei
05/09/2016
HIF-1α; Primary liver cancer; Prognosis; VEGF

The goal of this study was to investigate the expression of hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in primary liver cancer (PLC) and their association with prognosis. Tumor tissue, non-tumor tissue, and blood samples of 75 PLC patients were collected. Blood samples of 20 volunteers were also collected as healthy controls. Real-time ... more

L.Y. Guo; P. Zhu; X.P. Jin; L.Y. Guo; P. Zhu; X.P. Jin
05/09/2016
High-mobility group A2; miR-154; Non-small cell lung cancer; Prognosis; Proliferation

MicroRNA-154 (miR-154) is dysregulated in some human malignancies and is correlated with tumor progression. However, its expression and function in non-small cell lung cancer (NSCLC) remain unclear. Therefore, we explored the effects of miR-154 on NSCLC tumorigenesis and development. Using quantitative reverse transcription-polymerase chain reaction, we detected miR-154 expression in ... more

H.C. Zhuo; Y.F. Song; J. Ye; G.X. Lai; D.L. Liu
10/09/2015
Doppel gene; mRNA expression; Ovine; PRNP genotypes; Real-time quantitative RT-PCR

Doppel is a homologue of cellular prion protein (PrP)-like protein (PrPC). Different tissue samples were collected from the central nervous system plus four regions of lymphoid system, eleven regions of digestive tract and two reproductive organs from four ARR/ARQ and four ARH/ARQ sheep, genotypes of the PrP gene. Total RNA was isolated from these samples, and Doppel mRNA was ... more

C. Wang; C.L. Zhao; L. Liu; R. Wu; X.L. Zhang