Research Article

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04/26/2016
Bladder cancer; CYP1A2; Polymorphism; Risk

To date, no study has investigated the association between CYP1A2-163C/A polymorphism and bladder cancer risk in a Chinese population. Here, we extracted genomic DNA from peripheral white blood cells, and differentiated CYP1A2 alleles by polymerase chain reaction-based restriction fragment length polymorphism methods. Differences in genotype frequencies between the cases ... more

Y.L. Song; L. Wang; J.C. Ren; Z.H. Xu; Y.L. Song; L. Wang; J.C. Ren; Z.H. Xu; Y.L. Song; L. Wang; J.C. Ren; Z.H. Xu
04/28/2016
Esophageal cancer; Genetic variant; Polymorphism; Tumor necrosis factor-alpha
H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu; H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu; H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu; H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu; H. Zhao; H.W. Zhang; T. Zhang; X.M. Gu
07/14/2016
Meta-analysis; Monoamine oxidase B; Parkinson’s disease; Polymorphism

Although various individual studies have evaluated the correlation between monoamine oxidase B (MAOB), polymorphism, and Parkinson’s disease (PD), the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between the MAOB polymorphism and PD. Eligible studies were identified via databases such as ... more

J.J. Liu; W. Wang; M. Meng; C.S. Liang; J.W. Zhang
07/14/2016
Meta-analysis; Monoamine oxidase B; Parkinson’s disease; Polymorphism

Although various individual studies have evaluated the correlation between monoamine oxidase B (MAOB), polymorphism, and Parkinson’s disease (PD), the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between the MAOB polymorphism and PD. Eligible studies were identified via databases such as ... more

J.J. Liu; W. Wang; M. Meng; C.S. Liang; J.W. Zhang; J.J. Liu; W. Wang; M. Meng; C.S. Liang; J.W. Zhang
07/14/2016
Interleukin-6; Meta-analysis; Polymorphism; Psoriasis

Previous studies examining the association between interleukin-6 (IL-6) -174G/C polymorphism and psoriasis risk have produced inconsistent results. The aim of this study was to offer a comprehensive review of the association between IL-6 -174G/C polymorphism and psoriasis risk through a meta-analysis. Literature search of PubMed and Embase databases was conducted to identify all eligible ... more

G. Nie; C.L. Xie; Y.J. Cao; M.M. Xu; X. Shi; A.L. Zou; J.H. Qi; G. Nie; C.L. Xie; Y.J. Cao; M.M. Xu; X. Shi; A.L. Zou; J.H. Qi
06/24/2016
Chinese donkey; Microsatellite; Phylogenetic relationship; Polymorphism

To reveal the genetic diversity and phylogenetic relationships between Chinese donkey breeds, 415 individuals representing ten breeds were investigated using ten microsatellite markers. The observed number of alleles, mean effective number of alleles (NE), mean expected heterozygosity (HE), and polymorphic information content (PIC) of each breed and ... more

R.F. Zhang; W.M. Xie; T. Zhang; C.Z. Lei; R.F. Zhang; W.M. Xie; T. Zhang; C.Z. Lei
06/20/2016
Basigin gene; Esophageal cancer; miR-483-5p; Polymorphism

The aim of this study was to investigate the association between a functional variant of the basigin (BSG) gene, caused by a polymorphism (rs11473) at the miR-483-5p binding site, and the risk of esophageal squamous cell carcinoma (ESCC) in the Chinese population. The rs11473 polymorphism was genotyped in 624 esophageal cancer patients and 636 cancer-free age- and gender-matched ... more

H.Y. Li; Y.C. Liu; Y.H. Bai; M. Sun; L. Wang; X.B. Zhang; B. Cai; H.Y. Li; Y.C. Liu; Y.H. Bai; M. Sun; L. Wang; X.B. Zhang; B. Cai
06/20/2016
Cerebral infarction; Mononucleotide; Polymorphism; PPAR gamma

The variant of PPAR-g2 has been shown to promote the increase of carotid IMT in patients suffering from cerebral infarction and the Pro12Ala polymorphism in the peroxisome proliferator-activated receptorg2 (PPARg2) gene may be associated with cerebral infarction. However, due to the different genetic background, race, and regional variations of cerebral infarction ... more

X. Li; B.L. Zhang; X.G. Zhang; X.L. Su; X. Li; B.L. Zhang; X.G. Zhang; X.L. Su
06/20/2016
AMPD1; C34T; Essential hypertension; Malaysia; Polymorphism

The aim of this study was to determine whether C34T, a common polymorphism of the adenosine monophosphate deaminase 1 gene (AMPD1), is associated with essential hypertension (EH). We hypothesize that C34T is associated with the development of EH. A case-control design was used for this study. The DNA was extracted using a commercial kit from the whole blood of 200 patients with ... more

R. Nemati; J. Lu; V. Ramachandran; A. Etemad; M. Heidari; M.J. Yahya; R. Roozafzoon; P. Ismail; R. Nemati; J. Lu; V. Ramachandran; A. Etemad; M. Heidari; M.J. Yahya; R. Roozafzoon; P. Ismail
06/17/2016
Cytochrome P450; Lung cancer; Meta-analysis; Polymorphism; Risk

The aim of this meta-analysis was to assess the association between a polymorphism (-3860 G > A) in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer susceptibility. Relevant studies were retrieved from the PubMed and EMBase databases, and additionally evaluated for conformance with the inclusion criteria. The odds ratios (ORs) and their 95% confidence intervals (95%CIs) ... more

J. Ren; B.Z. He; T.S. Zhang; S.P. Lu; T. Yan; J. Ren; B.Z. He; T.S. Zhang; S.P. Lu; T. Yan

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