Research Article

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06/03/2016
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We conducted a case-control study to investigate the role of XPG gene polymorphisms (rs2094258, rs751402, and rs17655) in the development of breast cancer. Patients with breast cancer (320) and control subjects (294) were consecutively selected from the Zhongshan Hospital between April 2013 and January 2015. The genotyping of XPG rs2094258, rs751402, and rs17655 was performed using ... more

S.H. Ma; F.H. Ling; Y.X. Sun; S.F. Chen; Z. Li; S.H. Ma; F.H. Ling; Y.X. Sun; S.F. Chen; Z. Li
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ERCC1; ERCC2; Gastric cancer; Polymorphism; Treatment outcome

We conducted a prospective study to investigate whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer. Between January 2010 and December 2012, 246 patients with pathologically proven gastric cancer who were receiving platinum-based chemotherapy were recruited from the ... more

D.L. Zheng; G.D. Tang; Y.N. Chen; T. Zhang; M.B. Qin; D.L. Zheng; G.D. Tang; Y.N. Chen; T. Zhang; M.B. Qin; D.L. Zheng; G.D. Tang; Y.N. Chen; T. Zhang; M.B. Qin
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Gastric cancer; MicroRNA; Polymorphism; Review

MicroRNAs (miRNAs) are a class of small non-coding RNA molecules of about 22 nucleotides in length. miRNAs are highly conserved in both plants and animals, and function as gene regulators by binding to the 3'-untranslated region of target mRNAs for cleavage and/or translational repression. miRNA biogenesis, stability, and regulation of expression are strongly sequence dependent. Sequence ... more

B.W. Han; Z.H. Li; S.F. Liu; H.B. Han; S.J. Dong; H.J. Zou; R.F. Sun; J. Jia; B.W. Han; Z.H. Li; S.F. Liu; H.B. Han; S.J. Dong; H.J. Zou; R.F. Sun; J. Jia
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ERCC5; Gastric cancer; Polymorphism

We investigate the role of ERCC5 gene polymorphisms (rs17655 and rs751402) in the development of gastric cancer in a Chinese population. A total of 142 gastric cancer patients whose diagnoses were confirmed by pathology, and 274 control subjects were recruited from Tangshan Gongren Hospital between March 2013 and March 2015. Genotyping of ERCC5 rs17655 and rs751402 ... more

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ERCC5; Gastric cancer; Polymorphism; rs2094258; rs751402

We conducted a case-control study to assess the association between single nucleotide polymorphisms in the ERCC5 promoter (rs2094258 and rs751402) and development of gastric cancer in a Chinese population. This investigation included 184 patients with pathologically diagnosed gastric cancer and 206 healthy subjects recruited between October 2012 and December 2014. The genotyping ... more

J.J. Lu; H.Q. Zhang; P. Mai; X. Ma; X. Chen; Y.X. Yang; L.P. Zhang; J.J. Lu; H.Q. Zhang; P. Mai; X. Ma; X. Chen; Y.X. Yang; L.P. Zhang
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Gastric cancer; Interleukin-17; Polymorphism; rs2275913

The purpose of this hospital-based case-control study was to assess whether the interleukin (IL)-17 rs2275913 genetic variation can influence susceptibility to gastric cancer. Samples from a total of 202 gastric cancer patients and 237 controls were collected from the Linyi People’s Hospital between March 2013 and March 2015. The IL-17 rs2275913 gene polymorphism was identified by ... more

B.L. Xu; Y.T. Li; S.X. Dong; J. Qi; H.M. Feng; L. Zi; D.Y. Yang; B.L. Xu; Y.T. Li; S.X. Dong; J. Qi; H.M. Feng; L. Zi; D.Y. Yang
05/13/2016
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Here, we performed a case-control study to investigate the role of miR-146a, miR-149, and miR-196a2 polymorphisms in the development of gastric cancer using a hospital-based case-control design. A total of 186 gastric cancer patients and 186 control subjects were enrolled from Ren Ji Hospital between January 2012 and October 2014. MicroRNAs miR-146a, miR-149, and miR-196a2 were genotyped ... more

J.Y. Gu; L. Tu; J.Y. Gu; L. Tu
03/31/2014
NSCLC; SNPs; XPG; XRCC1; XRCC3

This study aimed to investigate the effects of single-nucleotide polymorphisms (SNPs) XRCC1 Arg194Trp, XRCC1 Arg280His, XRCC1 Arg399Gln, XRCC3 Thr241Met, XPG His104Asp, and XPG His46His in genes involved in the DNA-repair pathway on the outcomes of platinum-based chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). ... more

Z.Y. Jin; X.T. Zhao; L.N. Zhang; Y. Wang; W.T. Yue; S.F. Xu
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CSB; DNA repair-related genes; Prostate cancer; XPG

We aimed to investigate the association between genetic variants of the DNA repair genes XPG, CSB, XPC, CCNH, and MMS19L in the nucleotide excision repair (NER) pathway and risk of prostate cancer in a population in China. This study included 229 patients with newly diagnosed and histopathologically confirmed primary prostate cancer and 238 ... more

X.J. Zhang; P. Liu; F. Zhu
04/28/2016
16S rDNA; Pathogenicity island; Polymerase chain reaction; Polymorphism

Chromobacterium violaceum is a free-living Gram-negative bacillus usually found in the water and soil in tropical regions, which causes infections in humans. Chromobacteriosis is characterized by rapid dissemination and high mortality. The aim of this study was to detect the genetic variability among C. violaceum type strain ATCC 12472, and seven isolates from the ... more

A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa; A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa; A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa

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