Research Article

Related GMR Articles

12/21/2015
Clinical outcome; ERCC1; ERCC2; Gastric cancer; Polymorphism

We performed a study to investigate the role of ERCC1 (rs11615, rs2298881, and rs3212986) and ERCC2 (rs13181, rs238406, and rs1799793) polymorphisms in the prognosis of gastric cancer. A total of 346 patients with gastric cancer were recruited between May 2009 and May 2012. Single nucleotide polymorphism genotyping was performed using the Sequenom MassARRAY platform. The GA+ ... more

W.H. Yu; Y.X. Wang; J.Q. Guo; Y.L. Wang; J.S. Zheng; K.X. Zhu
12/17/2015
ERCC1; ERCC2; Gastric cancer; Overall survival; Polymorphism; Response to chemotherapy

We investigate whether three common polymorphisms in ERCC1 and ERCC2 are predictor factors for the chemotherapy response, as well as the clinic outcome of patients with gastric cancer. Between May 2011 and May 2013, 263 patients with gastric cancer who were newly diagnosed by histopathology were enrolled in our study. Genotyping of the ERCC1 rs11615 and rs3212986, ... more

G. Zhong; H.K. Li; T. Shan; N. Zhang
09/21/2015
EGFR; FISH; Metastasis; NSCLC

The aim of this study was to explore epidermal growth factor receptor (EGFR) gene amplification and its relationship with cancer invasion and metastasis in non-small cell lung cancer (NSCLC). EGFR amplification in 45 patients with NSCLC and 15 subjects with normal lung tissues was detected by fluorescence in situ hybridization. The relationship between EGFR ... more

X.F. Jia; J. Li; H.B. Zhao; J. Liu; J.J. Liu
03/30/2021
EGFR; Epidermal Growth Factor Receptor (ErbB-1; Her); Sinonasal cancer; SNSCC; Squamous cell carcinoma

Prognosis of sinonasal squamous cell carcinoma (SNSCC) depends on TNM (Tumor, Node, Metastasis) staging, histological manifestations, and activity of cell-surface receptors (p53, Ki67, EGFR − Epidermal Growth Factor Receptor (ErbB-1; Her1). EGFR is the best- studied transmembrane tyrosine kinase receptor. The intensity of tumor cells division and the rate of their ... more

N.D. Phuc; L.M. Ky; N.T. Binh; V.T.M. Thuc; N.T. Tuan; N.T.K. Van; T.X. Hai

Pages