Research Article

Related GMR Articles

Interleukin-10; Meta-analysis; Pediatric asthma; Polymorphism

The results of previous epidemiological studies exploring the relationship between interleukin-10 (IL-10) promoter polymorphisms and susceptibility to pediatric asthma are not consistent. Therefore, we have performed a systematic review and meta-analysis to provide a more convincing conclusion. Odds ratios (OR) with their 95% confidence intervals (CIs) were used to evaluate the ... more

Z.Y. Huang; B.J. Cheng; Y. Wan; C. Zhou; Z.Y. Huang; B.J. Cheng; Y. Wan; C. Zhou
Cancer; CTHRC1; Human tumors; Meta-analysis; Protein expression

The aim of this meta-analysis was to investigate the overall diagnostic and prognostic values of CTHRC1 expression in human cancer development. Based on the inclusion and exclusion criteria, 8 cohort studies were included in the meta-analysis. The data were extracted, and analyses were performed using a random-effects model. Summary odds ratios (ORs) and effect sizes (ESs) with 95% ... more

S.F. Wang; Z. Yin; J.J. Yin; W. Zhang; C.G. Dong; S.F. Wang; Z. Yin; J.J. Yin; W. Zhang; C.G. Dong
CYP1A1; Meta-analysis; Oral cancer; Polymorphism

Numerous studies regarding the association between the CYP1A1 MspI polymorphism and oral cancer risk in Asian populations have shown controversial results. To get a more precise estimation of this relationship, we conducted a comprehensive meta-analysis. PubMed, the Cochrane Library, Elsevier Science Direct, Web of Knowledge, the Chinese National Knowledge Infrastructure, VIP, ... more

J.L. Xu; R. Xia; L. Sun; X. Min; Z.H. Sun; C. Liu; H. Zhang; Y.M. Zhu; J.L. Xu; R. Xia; L. Sun; X. Min; Z.H. Sun; C. Liu; H. Zhang; Y.M. Zhu
Meta-analysis; Periodontitis; Polymorphism; Vitamin D receptor

Although a number of studies have been conducted to determine the association between vitamin D receptor (VDR) TaqI polymorphism and periodontitis in the Chinese population, this association remains elusive. To assess the influence of VDR TaqI polymorphism on the risk of periodontitis, a meta-analysis was performed in a Chinese population. Relevant studies were ... more

X.W. Ji; Y. Wang; C. Cao; L.J. Zhong; X.W. Ji; Y. Wang; C. Cao; L.J. Zhong
Meta-analysis; Peptidylarginine deiminase 4; Polymorphism; Rheumatoid arthritis

The correlation between the -104C/T polymorphism in the peptidyl arginine deiminase 4 (PADI4) gene and rheumatoid arthritis (RA) risk has been analyzed in several studies. However, the results are inconclusive and remain to be confirmed in several ethnic groups. The effect of the PADI4-104C/T polymorphism on RA risk in the Chinese population was evaluated in a meta- ... more

L.L. Gong; J. Chang; Y.M. Yang; L.L. Gong; J. Chang; Y.M. Yang
ERβ gene; Male infertility; RsaI polymorphism; Smoking habits

The estrogen receptor β (ERβ) gene plays an important role in the regulation of fertility in both males and females. The RsaI polymorphism in ERβis associated with male infertility in Caucasian patients. The aim of this study was to investigate the frequency of this polymorphism in the etiology of idiopathic male infertility and its ... more

B.M. Bordin; K.K.V.O. Moura
Azoospermia; Chromosomal polymorphisms; Male infertility; Pedigree analysis; Y chromosome microdeletion

The aim of this study was to evaluate the correlation between chromosomal polymorphisms and male infertility. The patients were diagnosed with azoospermia or oligospermiaby a semen analysis. Chromosomal analysis was performed on peripheral blood lymphocytes obtained from the patients, with standard G-banding and C-banding. Y chromosome microdeletions were detected by multiplex polymerase chain ... more

L.L. Li; D. Peng; R.X. Wang; H.B. Zhu; W.J. Wang; R.Z. Liu
AZF microdeletions; Klinefelter syndrome; Male infertility

We investigated azoospermia region microdeletions in male infertility patients with Klinefelter syndrome (KFS), as well as the association between azoospermia symptoms in patients with KFS and Y chromosome microdeletion polymorphisms. A total of 111 cases with male infertility confirmed to have KFS (47, XXY) and 94 fertile men were included in this study. Peripheral blood was drawn and ... more

L.X. Li; H.Y. Dai; X.P. Ding; Y.P. Zhang; X.H. Zhang; H.Y. Ren; Z.Y. Chen
Balanced translocation; Breakpoint; Chromosome 7; Genetic counseling; Male infertility

Balanced reciprocal translocations are associated with reproductive failure. Some reciprocal translocation carriers exhibit azoospermia or oligozoospermia, and an association exists between these chromosomal abnormalities and recurrent abortion. Previous reports have indicated the involvement of chromosome 7 translocations in male infertility and recurrent ... more

R.X. Wang; H.G. Zhang; Y. Pan; J.H. Zhu; F.G. Yue; L.T. Xue; R.Z. Liu; R.X. Wang; H.G. Zhang; Y. Pan; J.H. Zhu; F.G. Yue; L.T. Xue; R.Z. Liu