Research Article

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04/04/2016
Breast cancer; Meta-analysis; MicroRNA-10b; Prognostic factor

Many microRNAs (miRNAs) exhibit altered expression levels in cancers, and they may be considered as valuable prognostic biomarkers for cancers. Here we aimed to summarize the recent advances in miR-10b involvement in human breast cancer and analyze the predicting role of miR-10b for survival. We searched, Embase, and Wanfang databases to identify studies on the prognostic role of miR-10b ... more

N. Wang; P. Chen; L.P. Huang; T.Z. Wang; N. Wang; P. Chen; L.P. Huang; T.Z. Wang; N. Wang; P. Chen; L.P. Huang; T.Z. Wang
04/04/2016
Coffee intake; CYP1A2; Ethnicity; Meta-analysis; rs762551 SNP

The association between the single nucleotide polymorphism rs762551 in the cytochrome P450 family 1, subfamily A2 gene (CYP1A2) and caffeine consumption remains controversial. We conducted a meta-analysis to clarify this potential association. Twelve studies were selected from articles retrieved from the and Google Scholar databases, and the data were analyzed to determine the ... more

S. Denden; B. Bouden; H. Khelil; J. Ben Chibani; M.H. Hamdaoui; S. Denden; B. Bouden; H. Khelil; J. Ben Chibani; M.H. Hamdaoui; S. Denden; B. Bouden; H. Khelil; J. Ben Chibani; M.H. Hamdaoui
07/14/2016
Meta-analysis; Monoamine oxidase B; Parkinson’s disease; Polymorphism

Although various individual studies have evaluated the correlation between monoamine oxidase B (MAOB), polymorphism, and Parkinson’s disease (PD), the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between the MAOB polymorphism and PD. Eligible studies were identified via databases such as ... more

J.J. Liu; W. Wang; M. Meng; C.S. Liang; J.W. Zhang
07/14/2016
Meta-analysis; Monoamine oxidase B; Parkinson’s disease; Polymorphism

Although various individual studies have evaluated the correlation between monoamine oxidase B (MAOB), polymorphism, and Parkinson’s disease (PD), the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between the MAOB polymorphism and PD. Eligible studies were identified via databases such as ... more

J.J. Liu; W. Wang; M. Meng; C.S. Liang; J.W. Zhang; J.J. Liu; W. Wang; M. Meng; C.S. Liang; J.W. Zhang
07/14/2016
Interleukin-6; Meta-analysis; Polymorphism; Psoriasis

Previous studies examining the association between interleukin-6 (IL-6) -174G/C polymorphism and psoriasis risk have produced inconsistent results. The aim of this study was to offer a comprehensive review of the association between IL-6 -174G/C polymorphism and psoriasis risk through a meta-analysis. Literature search of PubMed and Embase databases was conducted to identify all eligible ... more

G. Nie; C.L. Xie; Y.J. Cao; M.M. Xu; X. Shi; A.L. Zou; J.H. Qi; G. Nie; C.L. Xie; Y.J. Cao; M.M. Xu; X. Shi; A.L. Zou; J.H. Qi
06/20/2016
Hepatocellular carcinoma; Meta-analysis; Methylation; Pathogenesis; RUNX3

The aim of this study was to elucidate the role of RUNX3 promoter methylation in the pathogenesis of hepatocellular carcinoma (HCC) among Asians. For this purpose, we performed a comprehensive search of Chinese and English language scientific literature databases using stringent selection criteria; ultimately, we identified relevant studies that specifically assessed the ... more

W. Lu; Y. Liu; L.L. Liu; P.H. Zhuang; W. Lu; Y. Liu; L.L. Liu; P.H. Zhuang
06/17/2016
Cytochrome P450; Lung cancer; Meta-analysis; Polymorphism; Risk

The aim of this meta-analysis was to assess the association between a polymorphism (-3860 G > A) in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer susceptibility. Relevant studies were retrieved from the PubMed and EMBase databases, and additionally evaluated for conformance with the inclusion criteria. The odds ratios (ORs) and their 95% confidence intervals (95%CIs) ... more

J. Ren; B.Z. He; T.S. Zhang; S.P. Lu; T. Yan; J. Ren; B.Z. He; T.S. Zhang; S.P. Lu; T. Yan
06/16/2016
Breast cancer; GSTP1; Meta-analysis; Polymorphism

Breast cancer (BC) is the most widespread cause of cancer-related deaths in women. Many published studies have assessed the association between the glutathione S-transferase P1 (GSTP1) rs1695 polymorphism and BC risk. However, the effect of the GSTP1 rs1695 polymorphism on BC risk has remained controversial. Therefore, this meta-analysis was conducted to obtain a ... more

M. Kuang; W. Xu; C.X. Cao; L.L. Shen; J. Chang; X.L. Zhang; J.F. Chen; C.J. Tang; M. Kuang; W. Xu; C.X. Cao; L.L. Shen; J. Chang; X.L. Zhang; J.F. Chen; C.J. Tang
06/10/2016
Meta-analysis; Polycystic ovary syndrome; Polymorphism; Tumor necrosis factor alpha

Previous studies have suggested that the tumor necrosis factor alpha (TNF-α) gene 308G/A polymorphism may be associated with polycystic ovary syndrome (PCOS) risk. However, this relationship is controversial. The present meta-analysis aimed to evaluate the correlation between the TNF-α308G/A polymorphism and susceptibility to PCOS. A systematic ... more

X.B. Liu; X.H. Deng; B. Zhou; L. Zhang; X.M. Niu; X.B. Liu; X.H. Deng; B. Zhou; L. Zhang; X.M. Niu
06/10/2016
Genetic variant; Lung cancer; Meta-analysis; XPG gene

It has been suggested that the xeroderma pigmentosum complementation group G (XPG) gene Asp1104His polymorphism is linked to susceptibility to lung cancer. However, the results from the published studies are contradictory rather than conclusive. With this meta-analysis, we aimed to achieve a better understanding of the effects of the XPG gene Asp1104His polymorphism on ... more

B. Zhou; X.M. Hu; G.Y. Wu; B. Zhou; X.M. Hu; G.Y. Wu

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