Research Article

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09/21/2015
Adiponectin; Coronary heart disease; Inflammatory factor; Ischemia factor; Osteoprotegerin

This study aimed to explore serum adiponectin and osteoprotegerin levels in patients with coronary heart disease (CHD) and their correlation with inflammatory and ischemia factors. From September 2010 to Augest 2010, 347 CHD patients were enrolled for a retrospective analysis. Serum lipoprotein phospholipase A2 (Lp-PLA2), hypersensitive C-reactive protein (hs-CRP), ischemia modified albumin ( ... more

H.L. Zhang; X. Jin
08/03/2015
Adiponectin; Adipose tissue; Migration; Preadipocyte; Proliferation; Wound healing

The purpose of this study was to investigate the mechanism behind adipose tissue wound healing (ATWH). The preadipocyte cell line 3T3-L1 was cultured and expression of adiponectin receptors (AdipoR1/2) was detected by immunohistochemistry and reverse transcription polymerase chain reaction. The concentration of adiponectin secreted at different cell densities was measured by enzyme- ... more

C.E. Jin; L. Xiao; Z.H. Ge; X.B. Zhan; H.X. Zhou
01/08/2016
Adiponectin; Meta-analysis; Nonalcoholic fatty liver disease; Polymorphism

Numerous epidemiological investigations have evaluated the association between adiponectin gene T45G polymorphism and risk of nonalcoholic fatty liver disease (NAFLD). However, the results of these studies have proven to be inconsistent. Therefore, we conducted a meta-analysis to obtain a more accurate estimation of this association. Published articles were retrieved from PubMed and Web ... more

W. Zhang; L.Q. Zhu; X.L. Huo; J. Qin; G.Y. Yuan; W. Zhang; L.Q. Zhu; X.L. Huo; J. Qin; G.Y. Yuan; W. Zhang; L.Q. Zhu; X.L. Huo; J. Qin; G.Y. Yuan
04/26/2016
Acute rejection; Cytokines; Liver transplantation; Single nucleotide polymorphism

Acute rejection (AR) recurrence after liver transplantation (LT) is one of the major complications that leads to chronic graft dysfunction. It has been reported that the polymorphisms in some cytokine genes are associated with human liver allograft rejection. This study mainly investigated the associations between polymorphisms in the genes encoding interleukin-10 (IL10), ... more

X.X. Zhang; R.J. Bian; J. Wang; Q.Y. Zhang; X.X. Zhang; R.J. Bian; J. Wang; Q.Y. Zhang; X.X. Zhang; R.J. Bian; J. Wang; Q.Y. Zhang
07/17/2015
Inflammation; Oxidative stress; Probucol; Spinal cord injury

To investigate the effects of probucol on the treatment of spinal cord injury in rat, 80 rats were randomly divided into two groups of 40: a group treated with probucol and a control group. Allen’s method was used to establish a rat model of spinal cord injury. After establishment, probucol (500 mg·kg-1·day-1) was intraperitoneally injected into the treatment group ... more

W.B. Zhu; Y.H. Wang; G.F. Sun; J.H. Wu
12/22/2015
Inflammation; Interleukin-10; Periodontal disease; Polymorphism

Because of the complex interaction between periodontal pathogens and the host defense system, periodontitis is considered an inflammatory disorder of bacterial etiology that results in periodontal tissue damage. Genetic mechanisms may interfere with the gene expression of important inflammation mediators, modulating the immunologic response of an individual. In this study, we evaluated ... more

R. Hannum; F.R. Godoy; A.S. da Cruz; T.C. Vieira; L.B. Minasi; deM. e Silva; C.C. da Silva; A.D. da Cruz
12/14/2015
Acute cerebral infarction; Danhong injection; Hemodynamics; Inflammation

The objective of the current study was to investigate effects of Danhong injection on hemodynamics, inflammatory cytokines, and the NF-κB pathway in acute cerebral infarction. In total, 246 patients with acute cerebral infarction were divided into control (N = 121) and observation (N = 125) groups based on treatment. The control group underwent conventional treatment, while the ... more

Y. Jiang; Y.J. Lian
10/27/2015
Brain natriuretic peptide; Hypoxia; Inflammation; Renal ischemia/reperfusion injury

Brain natriuretic peptide (BNP) has a protective effect on acute injury of the heart, brain, and lung. However, its role in acute kidney injury (AKI) remains unclear. The aim of this study was to investigate the effect of lyophilized recombinant human BNP (lrh-BNP) on AKI and the underlying molecular mechanisms. An experimental model for AKI was established using an ischemia/reperfusion ( ... more

X. Cao; H.Y. Xia; T. Zhang; L.C. Qi; B.Y. Zhang; R. Cui; X. Chen; Y.R. Zhao; X.Q. Li
11/29/2017
Immune; Inflammation; Melanoma; Microbial Dysbiosis; Probiotics
 Antibiotic-induced disruption of the intestinal microbiota
has serious consequences for human physiology. We conducted a
microbial dysbiosis animal model to study and directly provide evidence
for microbial dysbiosis contribution to malignant melanoma animal
model. Females C57BL/6 wild-type (WT) mice injected with a limiting
threshold ... more
X. Ren; X. Zhang; Y. Zhu; Y. Gamallat; A. Meyiah; S. Ma; Y. Xin
09/30/2020
Air pouch; Allergy; Araticum; Histamine; Inflammation; Ovalbumin

Annona sylvatica (Annonaceae) is a common medicinal plant used in folk medicine for fever and cough; it is found in several Brazilian states, including Mato Grosso do Sul. The local population uses A. sylvatica leaves for treating fever and cough; however, how this medicinal plant affects the patients is little understood. We ... more

M. Andrade-Silva; S.C. Cavalher-Machado; A.S.N. Formagio; R.S. Maris; O.Mde Lima Junior; S.B.V. de Mello; M.G.M.O. Henriques; A.C. Arena; C.A.L. Kassuya

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