Research Article

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06/17/2016
Exclusive alleles; Extraction; Fragmentation; Genetic diversity; Microsatellites; Schinus terebinthifolius

In the face of a possible loss of genetic diversity in plants due the environmental changes, actions to ensure the genetic variability are an urgent necessity. The extraction of Brazilian pepper fruits is a cause of concern because it results in the lack of seeds in soil, hindering its distribution in space and time. It is important to address this concern and explore the species, used ... more

S.V. Álvares-Carvalho; J.F. Duarte; T.C. Santos; R.M. Santos; R. Silva-Mann; D. Carvalho; S.V. Álvares-Carvalho; J.F. Duarte; T.C. Santos; R.M. Santos; R. Silva-Mann; D. Carvalho
12/07/2015
DNA barcode; ITS2; Medicinal plant; rpoC1; trnH-psbA

Plants have been used throughout human history for food and medicine. However, many plants are toxic, and cannot easily be morphologically distinguished from non-toxic plants. DNA identification solves this problem and is widely used. Nonetheless, plant DNA barcode identification faces a number of challenges, and many studies have been conducted to find suitable barcodes. The present ... more

N.A.A. Aziz; M.I. Ahmad; D.M. Naim
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Genetic variability; Medicinal plant; Myrtaceae

Myrcia ovata Cambess. (Myrtaceae) is a medicinal and aromatic plant that has analgesic, bactericidal and fungicidal properties. Even though this plant has economic potential, nothing is known about the variability and genetic diversity of this species. This information is necessary to establish conservation strategies and allow prospection of natural resources. The aim ... more

L.A.S. White; A.V.C. Silva; S.V. Álvares-Carvalho; R. Silva-Mann; M.F. Arrigoni-Blank; E.M.S. Souza; C.S. Almeida; D.A.C. Nizio; T.S. Sampaio; A.F. Blank
2016 Dec 23
DNA, Ribosomal Spacer; Haplotypes; Metabolome; Metabolomics; Polymorphism, Genetic; Rhodiola

Rhodiola plants are a valuable resource in traditional Chinese medicine. The objective of this study was to evaluate the correlation between ribosomal DNA internal transcribed spacer (ITS) sequences and the three active components in Rhodiola plants. For this, we determined ITS sequence polymorphisms and the concentrations of active components salidroside, tyrosol, and gallic acid in different ... more

D.J. Zhang; W.T. Yuan; M.T. Li; Y.H. Zhang
2017 Feb 16
Bayes Theorem; Casearia; Chloroplasts; Conservation of Natural Resources; Discriminant analysis; DNA, Chloroplast; Genetic variation; Genetics, Population; Haplotypes; Microsatellite Repeats

Casearia grandiflora (Salicaceae) is a typical Cerrado species adapted to disturbed environments, making it useful for restoration projects. Knowledge of genetic diversity is important for establishing conservation strategies for this species. This study aimed to compare chloroplast haplotype diversity and structure of C. grandiflora, under the assumption that protected areas hold greater ... more

M.F. Costa; A.A. Pereira; J.B. Pinheiro; M.I. Zucchi; A.S.F. Araújo; R.L.F. Gomes; S.E.S. Valente; M.E.A. Oliveira; A.C.A. Lopes
2017 Mar 22
Animals; Biomarkers; Chickens; China; Female; Genome-wide association study; Haplotypes; Linkage disequilibrium; male; Polymorphism, Single Nucleotide; Quantitative trait loci; Quantitative Trait, Heritable; Reproduction; Selective breeding

Reproductive traits have long been studied and have an important influence on chicken breeding. To identify quantitative trait loci affecting reproductive traits, a genome-wide analysis of a Chinese chicken breed was performed to analyze age at first egg body weight at first egg, first egg weight, egg weight at the age of 300 days, egg weight at the age of 462 days, egg number at the age of ... more

Q.C. Fan; P.F. Wu; G.J. Dai; G.X. Zhang; T. Zhang; Q. Xue; H.Q. Shi; J.Y. Wang
2017 Mar 16
Animals; China; DNA, Mitochondrial; Evolution, Molecular; Fishes; Genetics, Population; Haplotypes; Lakes; Phylogeny; Polymorphism, Genetic

Coilia ectenes is a commercially important fishery species in China. C. ectenes taihuensis is an endemic and dominant species found in Taihu Lake of China. When compared with C. ectenes, C. ectenes taihuensis lacks anadromous behavior, and can independently grow and reproduce in Taihu Lake. In this study, the mitochondrial DNA control region (D-loop) sequences were employed to investigate the ... more

J.J. Zhang; J.R. Duan; Y.F. Zhou; J.Y. Peng; D.A. Fang
2017 Mar 30
Aged; Aged, 80 and over; Alleles; Asian Continental Ancestry Group; Case-control studies; Ethnic groups; Gene frequency; Genetic predisposition to disease; Genetic variation; Haplotypes; Humans; male; Middle Aged; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt

AKT1, also known as v-akt murine thymoma viral oncogene homolog 1, is involved in the regulation of cell-survival and anti-apoptotic activities, which may affect the pathogenesis of various cancers. However, the association between genetic variants of AKT1 and the risk of developing prostate cancer has not been investigated before. This study investigated the associations between three ... more

J.M. Liu; S.H. Cheng; C. Xia; T. Deng; Y.C. Zhu; X. Wei; Z.L. Huang; B.H. Liao; D.Y. Luo; Y.G. Zhang; T. Jin; K.J. Wang; J. Huang; H. Li
2017 Mar 30
Alleles; Amelogenin; Asian Continental Ancestry Group; China; Chromosomes, Human, X; Chromosomes, Human, Y; DNA fingerprinting; Ethnic groups; Female; Forensic genetics; Gene frequency; Genetics, Population; Haplotypes; Humans; male; Microsatellite Repeats; Paternity; Polymorphism, Genetic

The sex-linked short tandem repeats (STR), Y-STR and X-STR, are important for autosomal STRs in forensic paternity testing. We evaluated the forensic parameters of 19 Y-STRs and 16 X-STRs in the Han population of Shandong province, China. A Goldeneye 20Y kit (DYS391, DYS389I, DYS390, DYS389II, DYS348, DYS456, Y-GATA-H4, DYS447, DYS19, DYS392, DYS393, DYS388, DYS439, DYS635, DYS448, DYS460, ... more

H.M. Gao; C. Wang; S.Y. Han; S.H. Sun; D.J. Xiao; Y.S. Wang; C.T. Li; M.X. Zhang
2017 Apr 05
Alleles; Brazil; Gene frequency; Genetic association studies; Haplotypes; Humans; Huntingtin Protein; Huntington Disease; Mutation; Trinucleotide repeat expansion

Huntington's disease (HD) is an autosomal dominant progressive neurodegenerative disorder caused by a dynamic mutation due to the expansion of CAG repeats in the HTT gene (4p16.3). The considered normal alleles have less than 27 CAG repeats. Intermediate alleles (IAs) show 27 to 35 CAG repeats and expanded alleles have more than 35 repeats. The IAs apparently have shown a normal phenotype. ... more

T.A. Apolinário; C.L.A. Paiva; L.A. Agostinho

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