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Laryngeal cancer remains one of the most common head and neck tumors. In the treatment of this disease, it is important to assess the overall survival when using transoral СО2 laser microsurgery. The aim of the research was to make an evaluation of treatment of patients with laryngeal cancer undergoing CO2 laser transoral microsurgery. Fifty ... more

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Abiotic stress; Cold; MYB; Rice; Transcription factor

The MYB-domain proteins exist universally across diverse organisms and regulate numerous processes during the plant life cycle. In the present research, a full-length MYB gene OsMYB511 was identified from rice seedlings through microarray data. Induction of OsMYB511 by cold stress was dramatic in japonica cultivar Jiucaiqing as compared to indica IR26. ... more

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Cold tolerance; ICE1 gene; Tomato; Transcription factor

The tomato plant (Solanum lycopersicum Mill.) is sensitive to cold, and low field temperatures can result in shortened growth periods and decreased crop yield. Transcription of CRT/DRE-binding factor (CBF) is regulated by INDUCER of CBF EXPRESSION1 (ICE1). CBF activates many downstream genes that confer cold tolerance on plants. ICE1 has been ... more

X.H. Yu; J.X. Juan; Z.L. Gao; Y. Zhang; W.Y. Li; X.M. Jiang
Abiotic stress; bZIP; Carrot; Evolution; Group A; Transcription factor

The basic-region/leucine-zipper (bZIP) family is one of the major transcription factor (TF) families associated with responses to abiotic stresses. Many members of group A in this family have been extensively examined and are reported to perform significant functions in ABA signaling as well as in responses to abiotic stresses. In this study, 10 bZIP factors in carrot were classified ... more

F. Que; G.L. Wang; Y. Huang; Z.S. Xu; F. Wang; A.S. Xiong
Haplotype; Maize; NAC; Salinity; Transcription factor

The maize NAC gene, encoding a NAC domain transcription factor, plays vital roles in the growth process of maize under abiotic stresses. To investigate the response of ZmNAC33 to salinity stress, we analyzed the expression of the ZmNAC33 gene in roots and leaves of three-leaf stage seedlings among maize inbred lines. The result showed that the expression of ZmNAC33 ... more

W. Liu; C. Zhang; S. Li; F. Jin; W. Li; X. Li
Adaptability; Factor analysis; G x E interaction; Stability; Unstructured variance

This study aimed to analyze the robustness of mixed models for the study of genotype-environment interactions (G x E). Simulated unbalancing of real data was used to determine if the method could predict missing genotypes and select stable genotypes. Data from multi-environment trials containing 55 maize hybrids, collected during the 2005-2006 harvest season, were used in this study. ... more

J.J. Nuvunga; L.A. Oliveira; A.K.A. Pamplona; C.P. Silva; R.R. Lima; M. Balestre
Factor analysis; Featured gene; Gene expression profile; Multivariate statistics

In this study, a software tool (IFGFA) for identification of featured genes from gene expression data based on latent factor analysis was developed. Despite the availability of computational methods and statistical models appropriate for analyzing special genomic data, IFGFA provides a platform for predicting colon cancer-related genes and can be applied to other cancer types. The ... more

C.H. Fu; S. Deng; J.H. Wu; X.Q. Wu; Z.H. Fu; Z.G. Yu; C.H. Fu; S. Deng; J.H. Wu; X.Q. Wu; Z.H. Fu; Z.G. Yu
Biometric; Selection; SNPs; Statistics

The aim of this study was to evaluate different methods used in genomic selection, and to verify those that select a higher proportion of individuals with superior genotypes. Thus, F2 populations of different sizes were simulated (100, 200, 500, and 1000 individuals) with 10 replications each. These consisted of 10 linkage groups (LG) of 100 cM each, containing 100 equally spaced markers ... more

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Artificial Intelligence; Discrimination; Similarity; Statistics

The correct classification of individuals is extremely important for the preservation of genetic variability and for maximization of yield in breeding programs using phenotypic traits and genetic markers. The Fisher and Anderson discriminant functions are commonly used multivariate statistical techniques for these situations, which allow for the allocation of an initially unknown ... more

I.C. Sant’Anna; R.S. Tomaz; G.N. Silva; M. Nascimento; L.L. Bhering; C.D. Cruz
ATP; ImmuKnow assay; Prognosis; Renal carcinoma

This study aimed to explore the clinical value of the CD4+ T cell ATP levels in patients with renal cell carcinoma through the application of the ImmuKnowTM-Cylex® assay. We recruited 104 patients with renal cancer who had undergone surgery at Fuzhou General Hospital from March 2009 to June 2012, and were subsequently treated by dendritic cell and ... more

K. Zheng; J.P. Zhang; J.M. Tan; W.Z. Wu; S.L. Yang; D.D. Ke