Research Article

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Biometric; Selection; SNPs; Statistics

The aim of this study was to evaluate different methods used in genomic selection, and to verify those that select a higher proportion of individuals with superior genotypes. Thus, F2 populations of different sizes were simulated (100, 200, 500, and 1000 individuals) with 10 replications each. These consisted of 10 linkage groups (LG) of 100 cM each, containing 100 equally spaced markers ... more

L.L. Bhering; V.S. Junqueira; L.A. Peixoto; C.D. Cruz; B.G. Laviola
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Idiopathic azoospermia; Idiopathic oligospermia; Pygo2 gene; SNPs

Male infertility is often associated with a decreased sperm count. The Pygo2 gene is expressed in the elongating spermatid during chromatin remodeling; thus impairment in PYGO2 function might lead to spermatogenic arrest, sperm count reduction, and subsequent infertility. The aim of this study was to identify mutations in Pygo2 that might lead to idiopathic oligospermia ... more

S.Q. Ge; J. Grifin; L.H. Liu; K.I. Aston; L. Simon; T.G. Jenkins; B.R. Emery; D.T. Carrell
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Body size; Haplotype; IGFBP-6; Mini-pig; SNPs

Insulin-like growth factor binding protein-6 (IGFBP-6) is a member of the IGFBP family, which is known to be a key factor in regulating the effect of insulin-like growth factor-2 (IGF-2) on the animal growth and development. Gene sequences of 3'-untranslated regions (UTR) and exon 4 of IGFBP-6 may influence the expression and proteolysis of IGFBP-6. In this study, 551 bp of the ... more

X.B. Fang; S.C. Liu; Q.Y. Wu; S.M. Li; Y.Y. Cheng; H.Y. Fu; C. Lu; D. Su; H. Yu; L.L. Hao
10/09/2015
Genetic diversity; Haplo-block structure; SNPs; Village chickens

This study investigated the haplo-block structure, haplotype sharing, and diversity in extensively raised chicken populations of Southern Africa. Two hundred ninety village chickens from Malawi (N = 30), South Africa (N = 132), and Zimbabwe (N = 128) were included in the study, from which 649, 2104, and 2442 haplo-blocks were observed, respectively. The majority of haplo-blocks were ... more

K.S. Khanyile; E.F. Dzomba; F.C. Muchadeyi
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Duck; Fatty acid composition; SCD1; Serum biochemical levels; SNPs

Stearoyl-coenzyme A desaturase 1 (SCD1) is the key limiting enzyme in the synthesis of monounsaturated fatty acids, and plays a crucial role in the regulation of oleic acid. In this study, 165 ten-week-old Cherry Valley ducks were used to investigate single nucleotide polymorphisms (SNPs) in the 5' regulatory region of the SCD1 gene, and their associations with duck serum ... more

W.G. Li; Y.Y. Zhang; D.D. Wang; W.G. Li; Y.Y. Zhang; D.D. Wang
10/24/2016
IFIH1; Meta-analysis; SLE; SLE clinical manifestations; SNPs

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder presenting heterogeneous clinical manifestations. A number of genes involved in SLE susceptibility are related to the type I interferon (IFN) pathway. IFN mediates innate immune responses and its increased levels contribute to the breakdown of peripheral tolerance. Interferon-induced helicase C ... more

deAzevêdo Silva; S.C. Lima; C. Addobbati; R. Moura; L.A.Cavalcanti Brandão; J.A.Trés Pancoto; E.A. Donadi; S. Crovella; P. Sandrin-Garcia
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Heat stress; MBV; Milk yield; Prolactin; SNPs

The association of single nucleotide polymorphisms (SNPs) within genes of the prolactin (PRL), growth hormone (GH) and insulin-like growth factor-I (IGF1) pathways with 305-day milk yield (MY305) were evaluated in heat-stressed Holstein cows. Ambient temperature and relative humidity were used to calculate a temperature-humidity index (THI), which revealed that ... more

H. Cordero; M.A.Sanchez Castro; Z. Algandar; L. Nevarez; G. Rincon; J.F. Medrano; S.E. Speidel; R.M. Enns; M.G. Thomas
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Breeding for water-deficit tolerance is fundamental to guarantee the sustainability of upland rice production, mainly due to the possibility of an increased frequency of drought episodes due to climate change. This work aimed to identify single nucleotide polymorphism (SNP) markers, derived from RNA sequencing (RNA-Seq), genome-wide association study (GWAS) and ... more

A.Faria Vieira; G.Feresin Pantalião; F.Martins Abreu; R.Dias Silveira; A.Letycia Ba Garcia; L.Gomide Neves; R.Pereira Vianello; A.Pereira Castro; C. Brondani
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Genetic association; Genotyping; Maternal line; SNPs; Sus scrofa domesticus

MC4R, FABP3 and DGAT1 are important genes related to productive and reproductive traits in pigs, such as food intake, growth rate, back fat thickness reduction and lactation. Selection of pigs for lean meat production may lead to losses in reproductive charcters because reduction of backfat thickness and low feed intake during the lactation phase ... more

V.S. Gondim; J.S. Soares; N.A.H. Lugo; N.B. Stafuzza; G.S. Vieira; R.R. Aspilcueta-Borquis; L.A.F. Pascoal; A.C.P. Silveira; H. Tonhati; R.C. Antunes
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Copy number of variations; Insertions / deletions; Ovis aries; Sheep; SNPs

We report the whole ram genome of Jordanian Awassi (Ovis aries), screened using the power of Illumina HiSeq sequencing technology, providing insights into the ram's genomic structure. Generated data will help in the assessment of naturally occurring genetic variation and population structure of this sheep breed using different structure variation markers. ... more

N. Haddad; H. Migdadi; R. Al-Atiyat; K. Jawasre; S. Awabdeh; W. Obeidat; R. AlOmari; M. Aldamra; H. Ababneh; M.J. Tabbaa; M. Brake; M. Farooq

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