Research Article

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08/19/2015
China; Conservation unit; Cytochrome b; Cytochrome C Oxidase Subunit I; Pachyhynobius shangchengensis

The evolutionary significant units (ESUs) of the salamander Pachyhynobius shangchengensis (Hynobiidae) in the Dabieshan mountains, southeastern China, were identified based on mitochondrial DNA data. We used methods for detecting cryptic species, such as the minimum spanning tree, the automatic barcode gap discovery, and the generalized mixed Yule-coalescent model; geographical ... more

L.N. Su; Y.Y. Zhao; X.M. Wu; H.F. Zhang; X.C. Li
2016 Dec 02
Adult; Aged; Aged, 80 and over; Asian People; China; Chromosome aberrations; Chromosomes, Human; Female; Humans; Karyotyping; Lymphoma, Non-Hodgkin; male; Middle Aged; Young Adult

The incidence of non-Hodgkin lymphoma (NHL) in China is increasing and is attracting attention as a topic of research. The percentage of NHL cases in ethnic Uighur people is also gradually increasing. We therefore recruited Uighur people with NHL to investigate the correlation between genetic alternations and clinical/pathological features in an attempt to determine their clinical significance ... more

L. Xu; X.G. Zou; X. Wang; A.B.L.M.T. Hairesa; J.J. Liu
2016 Dec 02
Actinin; Adult; Ankle Injuries; Asian People; China; Female; Gene frequency; Genetic association studies; Genetic predisposition to disease; Humans; male; Polymorphism, Single Nucleotide; Young Adult

In this study, we investigated the association between ACTN3 R577X polymorphism and non-acute ankle sprain by measuring the allele frequency and genotype distribution of ACTN3 in a Chinese Han population. We recruited 100 patients with non-acute ankle sprain and 100 healthy controls with no history of ankle injuries. Mass spectrometric analysis of single nucleotide polymorphism was used to ... more

B. Qi; J.Q. Liu; G.L. Liu
2016 Dec 02
Alcohol Oxidoreductases; China; Cloning, Molecular; Eucalyptus; Gene Expression Regulation, Plant; Lignin; Phylogeny; Plant Proteins; Plants, Genetically Modified; Tobacco

Cinnamyl alcohol dehydrogenase (CAD) catalyzes the final step in lignin biosynthesis. The genus Eucalyptus belongs to the family Myrtaceae, which is the main cultivated species in China. Eucalyptus urophylla GLU4 (GLU4) is widely grown in Guangxi. It is preferred for pulping because of its excellent cellulose content and fiber length. Based on GLU4 and CAD gene expression, a Eucalyptus variety ... more

B.W. Chen; Y.F. Xiao; J.J. Li; H.L. Liu; Z.H. Qin; Y. Gai; X.N. Jiang
2016 Dec 19
China; Chromosomes, Plant; Cotton Fiber; Genotype; Gossypium; Plant breeding; Polymorphism, Genetic; Quantitative trait loci

Upland cotton (Gossypium hirsutum L.) is an important cash crop that provides renewable natural fiber worldwide. Currently limited genetic base leads to a decrease in upland cotton genetic diversity. Multi-parent advance generation inter-cross (MAGIC) populations can be used to evaluate complex agronomic traits in crops. In this study, we developed an upland cotton MAGIC population. A total of ... more

D.G. Li; Z.X. Li; J.S. Hu; Z.X. Lin; X.F. Li
2016 Dec 19
Aged; Asian People; Carcinoma, Non-Small-Cell Lung; China; Female; Genetic predisposition to disease; Humans; Interferon-gamma; Interleukin-18; Lung Neoplasms; male; Middle Aged; Polymorphism, Single Nucleotide; Tumor necrosis factor-alpha

Lung cancer is one of the main causes of cancer-related mortality in males and females worldwide. A pleiotropic effect has been observed in the interleukin 18 gene (IL18); its effects include the activation of natural killer cell cytotoxicity and the promotion of the Th1 immune response through the alteration of the expression of interferon-γ and TNF-α in humans. IL18 is therefore involved in ... more

W.Y. Gan; H.M. Li; Y.G. Zhang; C.M. Li; Y. Wang
2016 Dec 19
Adult; China; Female; Fetal Growth Retardation; Folic acid; Folic Acid Deficiency; Gestational age; Homocysteine; Humans; Infant, Newborn; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

Deficiencies in nutrients such as folic acid and vitamin B12 may play a role in fetal growth restriction (FGR). However, whether folic acid, vitamin B12, or homocysteine is associated with FGR in Chinese populations remains unclear. This study investigated the relationship between these nutrient deficiencies and FGR in pregnant Chinese women. We selected 116 mother and infant pairs, and ... more

H.L. Jiang; L.Q. Cao; H.Y. Chen
2016 Dec 23
Alleles; China; Genetic variation; Microsatellite Repeats; Zea mays

Because of their local adaptation and economic factors that limit the adoption of commercial hybrids, farmer-saved maize landraces are still grown over a considerable area concentrated in southwest China. To evaluate the potential of using maize landraces, the germplasm characteristics of 96 landraces from southwest China were evaluated at phenotypic, cellular, and molecular levels. The ... more

F.B. Chen; Q.L. Yao; H.F. Liu; P. Fang
2017 Feb 08
Alleles; Asian People; Case-control studies; China; Connexin 26; Connexins; Deafness; Female; Genotype; Humans; Odds Ratio; Polymorphism, Genetic; Pregnancy; Risk; Sequence Deletion

Congenital deafness is a serious and irreversible condition in humans. The GJB2 gene is implicated in the pathogenesis of autosomal recessive nonsyndromic hearing loss. Its 235delC and 30-35delG polymorphisms are reported to be associated with risk of hereditary deafness. However, the effect of the interaction between GJB2 235delC and 30-35delG and environmental factors on congenital deafness ... more

Y. Xiong; M. Zhong; J. Chen; Y.L. Yan; X.F. Lin; X. Li
2017 Feb 23
Adult; Asian People; China; Female; Gene frequency; Genetic predisposition to disease; Genotype; Humans; Interleukin-10; Interleukin-6; Logistic Models; Odds Ratio; Polymerase chain reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pre-eclampsia; Pregnancy; Promoter Regions, Genetic; Risk factors; Young Adult

Preeclampsia is a common condition unique to pregnant women. Previous studies have suggested that several cytokines may contribute to defective placental invasion and endothelial damage in this condition. We investigated the influence of four single nucleotide polymorphisms (SNPs) in the promoters of IL-6 (-572G/C, -597G/A, and -174G/C) and IL-10 (-592A/C) on susceptibility to preeclampsia in ... more

D.M. Fan; Y. Wang; X.L. Liu; A. Zhang; Q. Xu

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