Research Article

Related GMR Articles

01/24/2014
Adult; Emergence agitation; Isoflurane; Propofol

Distal radius fracture is a common wound. It is reduced by surgery under anesthesia. Emergence agitation can often occur after anesthesia. It is associated with increased morbidity and hospital costs. However, there have been almost no reports in the medical literature on the occurrence of emergence agitation in adults. This study aimed to compare emergence agitation between isoflurane ... more

G.Y. Liu; Z.Q. Chen; Z.W. Zhang
06/26/2015
4; 5-trisphosphate receptors; Apoptosis; Calcium; Endoplasmic reticulum; Inositol 1; Isoflurane

Isoflurane can induce widespread cytotoxicity. We hypothesized that isoflurane induces apoptosis partly by causing excessive calcium release from the endoplasmic reticulum (ER) via direct activation of inositol 1,4,5-trisphosphate receptors (IP3R). Rat pheochromocytoma cells cultured for seven days with nerve growth factor were divided into four groups: control group (C), IP ... more

W.H. Zhai; J. Zhao; S.P. Huo; X.G. Chen; Y.D. Li; Z.L. Zhang; L.L. Yu; S. Song; Q.J. Wang
09/23/2016
Apoptosis; Bcl-2; Caspase-3; Chondrocytes; Hip dislocation

This study aimed to determine whether abnormal apoptosis is present in acetabular cartilage in early developmental dislocations of the hip (DDH), and if so, whether it is correlated with the expression of caspase-3 and Bcl-2. DDH was induced in 24 4-week-old New Zealand white rabbits. Acetabular cartilage specimens from the experimental and control groups were stained with hematoxylin ... more

L.J. Ding; Y.L. Liu; G. Ma; Y.Q. Jia; Y.S.H. Wei; X.M. Liu; L.J. Ding; Y.L. Liu; G. Ma; Y.Q. Jia; Y.S.H. Wei; X.M. Liu
10/17/2016
Caspase-3; Citrate; Ventricular arrhythmia

Ischemia/reperfusion (I/R) injury often triggers ventricular arrhythmia. Citrate binds calcium ions, forming a soluble calcium citrate complex that may reduce I/R injury by affecting calcium ion concentration. We tested the effects of citrate pretreatment on ventricular heart rate and related factors in a rat I/R model. Fifty male Sprague Dawley rats weighing 350- ... more

Q. Lu; Z.G. Li; N. Zhou; Z.G. Gong; J.Q. Jiang; Z.N. Chen; Q.J. Jiang; Y. Peng; S.F. Ding
12/17/2015
Meta-analysis; Polymorphism; Tumor necrosis factor-α; Vitiligo

Several case-control studies have been conducted to investigate the association between the tumor necrosis factor-α (TNF-α)-308G/A polymorphism and vitiligo risk. However, the results of these studies are inconsistent; therefore, we attempted to comprehensively evaluate the association between TNF-α-308G/A polymorphism and vitiligo risk via a meta-analysis. Studies reporting the ... more

G. Nie; J.H. Qi; C.W. Huang; T. Yang; N. Shi; Y.J. Chen
12/02/2015
Case-control study; Crohn’s disease; Meta-analysis; Polymorphism; Tumor necrosis factor-α

We investigated the associations between 2 major tumor necrosis factor-α (TNF-α) polymorphisms, rs1799724 C>T and rs1800629 G>A, and the susceptibility to Crohn’s disease (CD) using a meta-analysis framework. The PubMed, EBSCO, Ovid, Wiley, Web of Science, WANFANG, and VIP databases (last updated search in October 2014) were comprehensively searched for relevant ... more

Y.Q. Mao; S.Q. Dong; M. Gao
10/02/2015
Glioma invasiveness; Heat shock factor-1; HSF1; Thermotherapy; TNF-α; Tumor necrosis factor-α

Thermotherapy has been proven to be effective for the treatment of various tumors, including glioma. We determined whether tumor necrosis factor-alpha (TNF-α) is involved in the regulation of the biological processes of glioma development. Reverse transcription-polymerase chain reaction (RT-PCR) and immunocytochemistry were used to investigate the levels of TNF-α mRNA and heat shock ... more

L.J. Qin; T. Zhang; Y.S. Jia; Y.B. Zhang; Y.X. Zhang; H.T. Wang
09/09/2016
Differentiation; Growth factor progranulin; Osteoclast; Rheumatoid arthritis; Tumor necrosis factor-α

Tumor necrosis factor-α (TNF-α) stimulates osteoclast differentiation and suppresses osteoblast differentiation, leading to bone loss and decreased bone mass in local inflammation areas in patients with rheumatoid arthritis. The growth factor progranulin (PGRN) is expressed in various types of cells and play crucial roles in the pathogenesis of atherosclerosis and arthritis by blocking ... more

N. Wang; J. Zhang; J.X. Yang; N. Wang; J. Zhang; J.X. Yang
10/24/2016
Gene polymorphism; Osteoarticular tuberculosis; Prognosis; Tumor necrosis factor-α

This study investigated the association of tumor necrosis factor-α (TNF-α)-308, -238, and -863 polymorphisms with osteoarticular tuberculosis (OA-TB) prognosis in a Hebei population. Genomic DNA was extracted from venous blood samples of 120 OA-TB patients and 100 healthy volunteers. TNF-α-308, -238, and -863 were analyzed by PCR-restriction ... more

Y.J. Lv; S.J. Liu; W.N. Hu; G.P. Zhang; Q.Y. Ren; L.D. Zheng; Y.C. Zhang; R.Q. Li; Z.K. Zhang; Y.J. Lv; S.J. Liu; W.N. Hu; G.P. Zhang; Q.Y. Ren; L.D. Zheng; Y.C. Zhang; R.Q. Li; Z.K. Zhang; Y.J. Lv; S.J. Liu; W.N. Hu; G.P. Zhang; Q.Y. Ren; L.D. Zheng; Y.C. Zhang; R.Q. Li; Z.K. Zhang