Research Article

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Cancer risk; Polymorphism; Renal cell carcinoma; Vascular endothelial growth factor

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Microwave ablation; Non-small cell lung cancer; Vascular endothelial growth factor

We aimed to analyze the changes of serum vascular endothelial growth factor (VEGF) before and after microwave ablation (MWA) in patients with stage IIIB-IV non-small cell lung cancer (NSCLC), and to observe the effects of MWA combined with chemotherapy on short-term therapeutic efficacy and long-term survival. Concentrations of serum VEGF in 20 healthy subjects were considered as controls ... more

Y.H. Sun; P.Y. Song; Y. Guo; M. Pang; W.N. He; W.H. Zhang; L.J. Sheng
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We conducted a case-control study in a Chinese population to assess whether 5 common single-nucleotide polymor­phisms in the vascular endothelial growth factor gene (VEGF) affect the risk of renal cell carcinoma (RCC). The study population in­cluded 266 RCC patients who were newly diagnosed and histologi­cally confirmed to have RCC as well as 532 cancer-free controls. Genotyping ... more

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Endothelial cell; ERK MAPK; Extracorporeal cardiac shock; Vascular endothelial growth factor

Extracorporeal cardiac shock wave (SW) therapy is an effective, safe, and non-invasive therapeutic strategy for severe coronary artery disease. Shock wave therapy might affect cardiac tissues because of its ability to promote angiogenesis. In this report, we investigated if the up-regulation of vascular endothelial growth factor (VEGF) by SW therapy is involved in cell proliferation in ... more

Y.Z. Peng; K. Zheng; P. Yang; Y. Wang; R.J. Li; L. Li; J.H. Pan; T. Guo
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HIF prolyl-hydroxylase-2; Human chorionic gonadotropin; Hypoxia-inducible factor-1a; Luteal cells; Vascular endothelial growth factor

Vascular endothelial growth factor (VEGF)-dependent angiogenesis plays a crucial role in corpus luteum formation and its functional maintenance in mammalian ovaries. We recently reported that activation of hypoxia-inducible factor (HIF)-1α signaling contributes to the regulation of VEGF expression in luteal cells (LCs) in response to human chorionic gonadotropin (HCG). We examined whether HIF ... more

Z.H. Zhang; D.Z. Yin; X.S. Pang; Z.C. Wang
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Immunohistochemistry; Magnetic resonance perfusion weighted imaging; Radiation-induced brain injury; Vascular endothelial growth factor

We used magnetic resonance perfusion weighted imaging and pathological evaluation to examine different stages of radiation-induced brain injury and to investigate the correlation between the relative cerebral blood volume (rCBV) ratio and vascular endothelial growth factor (VEGF). Thirty adult rats were randomly divided into 2 groups: control and radiation group. The control group was not ... more

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Osteosarcoma; Polymorphism; Vascular endothelial growth factor

We conducted a case-control study to assess the role of vascular endothelial growth factor (VEGF) -634G/C, +936C/T, and +1612G/A genetic variations in the development of osteosarcoma in a Chinese population. This hospital-based case-control study examined 130 patients with osteosarcoma and 130 age- and gender-matched healthy controls from March 2011 and March 2013. Polymerase ... more

G.L. Hu; G. Ma; J.H. Ming
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Meta-analysis; Polymorphism; Psoriasis; Vascular endothelial growth factor

The aim of this study was to explore whether vascular endothelial growth factor (VEGF) polymorphisms confer susceptibil­ity to psoriasis. Meta-analyses were conducted to examine the asso­ciations between the +405 C/G, -460 C/T, -1154 A/G, and -2578 A/C polymorphisms of VEGF and psoriasis using allele contrast and reces­sive, dominant, and additive models. Seven studies ... more

Y.H. Lee; G.G. Song

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