Research Article

Related GMR Articles

06/18/2015
Differentially expressed genes; Geese; Ovary; Transcriptome

Geese are an economically important poultry species worldwide. Their superior meat production performance and meat qual­ity make them a popular food. However, they are not bred worldwide because their poor laying capacity increases farming costs. To gain a global view of the genes that are differentially expressed between pre-laying (P) and laying (L) periods and to develop a database ... more

N. Ding; Q. Han; X.Z. Zhao; Q. Li; J. Li; H.F. Zhang; G.L. Gao; Y. Luo; Y.H. Xie; J. Su; Q.G. Wang
11/18/2013
Genetic diversity; Macrobrachium nipponense; Microsatellite marker; Yellow river

To assess the genetic status of this species, the genetic diversity of wild Macrobrachium nipponense from seven geographic locations in the Yellow River basin were investigated using 20 polymorphic microsatellite DNA loci. The genetic diversity between populations was indicated by the mean number of alleles per locus and mean observed heterozygosity (H) and the expected H, which ... more

H. Qiao; D. Lv; S.F. Jiang; S.M. Sun; Y.S. Gong; Y.W. Xiong; S.B. Jin; H.T. Fu
05/18/2015
Broad-complex; cDNA; Macrobrachium nipponense; Metamorphosis; Real-time quantitative polymerase chain reaction

Broad-Complex (BR-C) is an early ecdysone-responsive gene encoding a family of zinc-finger transcription factors. In this study, we isolated the full-length cDNA of a BR-C homolog from the testes of the oriental river prawn (Macrobrachium nipponense), according to established expressed sequence tag information, using the rapid amplification of cDNA ends ... more

S.F. Jiang; Y.P. Zhang; S.M. Sun; Y.S. Gong; Y.W. Xiong; H. Qiao; W.Y. Zhang; S.B. Jin; H.T. Fu
09/13/2013
Arabidopsis; Differentially expressed genes; Drought; Microarray; Rewatering

Drought is a major limiting factor in crop production. Rewatering is a process opposite to drought, allowing plants to recover to their normal physiological state. To understand more thoroughly the set of genes involved in plant response to drought, we comparatively and jointly analyzed the microarray data of drought and rewatering experiments in Arabidopsis. A total of 3833 ... more

Z.H. Xu; W.R. Wu
12/12/2014
Bioinformatics; Differentially expressed genes; Leukemia

The purpose of this study was to identify differentially expressed genes and analyze biological processes related to leukemia. A meta-analysis was performed using the Rank Product package of Gene Expression Omnibus datasets for leukemia. Next, Gene Ontology-enrichment analysis and pathway analysis were performed using the Gene Ontology website and Kyoto Encyclopedia of Genes and Genomes ... more

Z.Y. Zhang; R.Q. Xu; T.J. Guo; M. Zhang; D.X. Li; X.Y. Lu
11/11/2014
Astrocytes; Differentially expressed genes; Functional analysis; Module analysis; Optic nerve

Microarray data of astrocytes extracted from the optic nerves of donors with and without glaucoma were analyzed to screen for differentially expressed genes (DEGs). Functional exploration with bioinformatic tools was then used to understand the roles of the identified DEGs in glaucoma. Microarray data were downloaded from the Gene Expression Omnibus (GEO) database, which contains 13 ... more

Y. Wu; W.D. Zang; W. Jiang
09/29/2014
Breast cancer; Differentially expressed genes; Gene coexpression network analysis; Pathway analysis

The aim of this study was to identify key genes related to invasive ductal carcinoma (IDC) of the breast by analyzing gene expression data with bioinformatic tools. Microarray data set GSE31138 was downloaded from Gene Expression Omnibus, including 3 breast cancer tissue samples and 3 normal controls. Differentially expressed genes (DEGs) between breast cancer and normal control were ... more

J.L. Huan; X. Gao; L. Xing; X.J. Qin; H.X. Qian; Q. Zhou; L. Zhu
04/25/2014
B cell; Bone mineral density; Differentially expressed genes; Enrichment analysis; Functional analysis

We searched for key genes that could accurately predict bone mineral density. The gene expression profile GSE7429 was downloaded from the Gene Expression Omnibus database, which includes 20 samples, 10 with high and 10 with low bone mineral density. The differentially expressed genes (DEGs) were identified with packages in R language. Further, BLASTX was used to obtain COG function ... more

Y. Chen; R.G. Xia
03/17/2014
Differentially expressed genes; Functional enrichment analysis; Interaction network; Multiple trauma; Pathway analysis; Sepsis

The purpose of this study was to identify critical genes associated with septic multiple trauma by comparing peripheral whole blood samples from multiple trauma patients with and without sepsis. A microarray data set was downloaded from the Gene Expression Omnibus (GEO) database. This data set included 70 samples, 36 from multiple trauma patients with sepsis and 34 from multiple trauma ... more

S.C. Ji; Y.T. Pan; Q.Y. Lu; Z.Y. Sun; Y.Z. Liu
01/03/2014
Differentially expressed genes; Endothelial progenitor cells; Folic acid; Immune response; Type 1 diabetes mellitus

We investigated the effects of type 1 diabetes mellitus (T1DM) on endothelial progenitor cells (EPCs) at the molecular level and assessed the therapeutic potential of folic acid (FA) in DM. We downloaded the gene expression profile of the EPCs from T1DM patients before and after treatment with FA and from healthy controls. We identified the differentially expressed genes (DEGs) in the ... more

D.N. Fang; X.D. He; X.H. Li; H. Jia; P.Y. Li; Q. Lu; Z. Quan; Q.L. Wang

Pages