Research Article

Related GMR Articles

03/30/2015
Cardiovascular events; Hemodialysis; IL-6; Polymorphism

We aimed to investigate the role of IL-6 polymorphism on the development of cardiovascular events and coronary artery disease in patients receiving hemodialysis. Blood samples were collected from 216 patients receiving hemodialysis treatment. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to genotype IL-6 -634C/G, -174G/C and -572C/G. By ... more

Y. Song; H.D. Gu; Y. He; J.W. Wang
03/30/2015
Fatty acid synthase gene; Meat quality traits; Polymorphism; Yak

Fatty acid synthase (FASN) is a key enzyme in fatty acid anabolism that plays an important role in the fat deposit of eukaryotic cells. Therefore, in this study, we detected 2 novel single-nucleotide polymorphisms (SNPs) in the FASN gene in 313 adult individuals of Datong yak using polymerase chain reaction-single strand conformation polymorphism and DNA sequencing techniques. SNP ... more

M. Chu; X.Y. Wu; X. Guo; J. Pei; F. Jiao; H.T. Fang; C.N. Liang; X.Z. Ding; P.J. Bao; P. Yan
03/30/2015
Ischemic stroke; miR-149; Polymorphism

Clinical and experimental data have demonstrated that genetic factors play an important role in determining the susceptibility to ischemic stroke (IS). The present study was performed to clarify the association between the pre-microRNA-149 (miR-149) single nucleotide polymorphism rs71428439 and the risk of IS in the Jiangsu Han population. Polymerase chain reaction and restriction ... more

Q.Y. Chen; N. Liu; J. Ma; Y. Fang; Y. Cao; H. Li; Y.C. Liu
03/30/2015
Chinese; Metabolic syndrome; Obesity; Polymorphism; Type 2 diabetes

Metabolic syndrome (MetS) includes obesity, dyslipidemia, elevated blood pressure, and dysglycemia. Subjects with type 2 diabetes (T2D) exhibit features of MetS. The etiology of MetS is complex, involving both environmental and genetic factors. In this study, we examined the role of specific candidate genetic variants on the severity of MetS in T2D subjects. A total of 240 T2D subjects ... more

Y.L. Chen; D. Pei; Y.J. Hung; C.H. Lee; F.C. Hsiao; C.Z. Wu; J.D. Lin; C.H. Hsu; J.B. Chang; C.H. Hsieh
03/30/2015
All hermaphrodites; Phylogenetic analysis; Polymorphism; Simple sequence repeat

The papaya (Carica papaya L.) is one of the most important economic tropical fruits in the world, and the hermaphrodite is the preferred type in field cultures. We analyzed the sexual ratio of offspring from the cultivar ‘Taiwan Seed Station No. 7’ (T7) by a self-cross and its cross with Taichung Sunrise (TS). Female progeny from the T7 self-crossing were not observed. This ... more

C.T. Chiu; C.W. Wang; F.C. Chen; S.W. Chin; C.C. Liu; M.J. Lee; W.C. Chung; Y.W. Chien; H.J. Chang; C.Y. Lee
03/20/2015
Angiotensin-converting enzyme; Coronary artery disease; Polymorphism

We investigated whether the insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene and serum ACE levels are associated with traditional risk factors of coronary artery disease (CAD). We enrolled 250 individuals without CAD and 750 individuals suffering from CAD who were angiographically diagnosed. Biochemical risk factors, the ACE (I/D) gene ... more

S. Sahin; K. Ceyhan; I. Benli; H. Ozyurt; E. Naseri; M.M. Tumuklu; L. Aydogan; A.O. Elalmis; A.F. Ozugurlu; O. Onalan
03/13/2015
Osteosarcoma; Polymorphism; RECQL5

In this study, we investigated the association between a RECQL genetic polymorphism and osteosarcoma in a Chinese population. We selected rs820196 in the RECQL5 gene and genotyped 185 patients with osteosarcoma and 201 age- and gender-matched non-cancer controls. We found that the CC genotype was more frequent in the osteosarcoma group compared to the control group (P = ... more

Y.Z. Dong; Y.X. Huang; T. Lu
03/13/2015
EGFR; ERBB1; Gastric cancer; Polymorphism

Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with tyrosine-kinase activity that plays an important role in multiple cellular functions. EGFR overexpression has been observed in several types of tumors and it is significantly associated with disease stage, survival, prognosis, and progression of cancer. The polymorphisms -216G>T, -191C>A, and (CA)n ... more

J.H. Torres-Jasso; M.E. Marín; E. Santiago-Luna; J.C. Leoner; J. Torres; M.T. Magaña-Torres; F.J. Perea; B. Ibarra; J.Y. Sánchez-López
03/13/2015
Microsatellite markers; Pachycrepoideus vindemmiae; Polymorphism

The parasitoid wasp Pachycrepoideus vindemmiae (Rondani) is a common pupal parasitoid of many fly pests that is distributed worldwide. This organism can be used for biological control in orchards or livestock farms. Identifying polymorphic microsatellite loci would be useful for analyzing the population genetic structure of the parasitoid. In the current study, based on a ... more

W. Chen; L. Fang; J.L. Liu; Z. He; H.Y. Hu
03/13/2015
Gene; Liver X receptor α; Polymorphism; Stroke

We examined the relationship between the liver X receptor α gene (LXRα) polymorphism and the susceptibility to stroke. We utilized the single fluorescent-labeled probe technique to detect the genotype of rs12221497 in the LXRα gene in 400 stroke patients and 400 healthy control subjects. The difference in genotype distribution between the 2 groups was analyzed using the ... more

J.S. Yang; J.J. Hao; S.S. Wang; Z.F. Zhu; Q. Fang; H. Bao; H.P. Zhang

Pages