Research Article

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Protein and DNA polymorphismswere surveyed among seven accessions of wild fenugreek (Trigonellafoenum-graecum L.) to estimate their genetic diversity and relationships. Samples were obtained from diverse ecogeographical areas in Saudi Arabia and Yemen. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis of seed storage protein showed genetic variations ... more

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Microsatellite; Molecular markers; Polymorphism; Portunus trituberculatus

The Swimming crab Portunus trituberculatus (Portunidae) is an important economically food species. To provide molecular markers for P. trituberculatus, we isolated and characterized polymorphic microsatellite markers. We developed a 5'-anchored genomic library of P. trituberculatus DNA, and derived 45 positive clones. We designed 30 pairs of primers from the ... more

L.P. Ren; Y. Qin; X.C. Li; Y.N. Sun; R.X. Wang
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Fatty acid composition; Insertion/deletion mutation; Polymorphism; Simmental bulls; Snow Dragon black cattle; SREBP1 gene

The sterol regulatory element binding factor 1 gene (SREBP1) plays an important role in the biosynthesis of fatty acids and cholesterol, and in lipid metabolism. The objective of this study was to investigate the effect of genetic polymorphisms of SREBP1 on the fatty acid composition of muscle and carcass traits in Simmental bulls and Snow Dragon black cattle. The 84-bp ... more

L. Xu; L.P. Zhang; Z.R. Yuan; L.P. Guo; M. Zhu; X. Gao; H.J. Gao; J.Y. Li; S.Z. Xu
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Chemokine; Gene; Inflammation; OSCC; Polymorphism

We aimed to evaluate the effect of genetic variants of the chemokine C-C motif receptor (CCR5) in the pathogenesis of oral squamous cell carcinoma (OSCC). A total of 127 patients diagnosed with OSCC and 104 healthy individuals were included in the study. The polymorphisms CCR5 59029 and CCR5-delta32 were assessed with the polymerase chain reaction-restricted fragment length polymorphism ( ... more

C.R. Tanyel; Z.B. Cincin; B. Gokcen-Rohlig; K. Bektas-Kayhan; M. Unur; B. Cakmakoglu
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High-altitude adaptation; Hypoxia adaptation; Polymorphism; Vascular endothelial growth factor A (VEGF-A); Yak

Vascular endothelial growth factor-A gene (VEGF-A) is a key regulator of angiogenesis and an endothelial cell mitogen that plays an important role in high-altitude adaptation. In this study, we detected 2 novel single-nucleotide polymorphisms (SNPs) of VEGF-A by screening for genetic variation in 700 individuals of 3 domestic Chinese yak breeds - namely Gannan (GN), ... more

X.Y. Wu; C.N. Liang; X.Z. Ding; X. Guo; P.J. Bao; M. Chu; W.B. Liu; P. Yan
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Dactylopiidae; Genetic markers; Opuntia ficus indica; Polymorphism

The carmine cochineal Dactylopius opuntiae is a key pest in productive fields of forage cactus in Pernambuco, Brazil. Species identification by means of molecular markers assists in understanding the genetic profile, underpins morphological characterization, and supports the monitoring of populations in integrated management programs designed to control this pest. We evaluated ... more

D.M.P. Silva; A.Cdo E.S. Mergulhão; L.V. de Medeiros; M.V.B. Figueiredo; H.A. Burity
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EPHX1 gene; Esophageal cancer; Meta-analysis; Polymorphism

Epoxide hydrolases metabolize exogenous chemicals, including carcinogens such as polycyclic aromatic hydrocarbons. The relationship between microsomal epoxide hydrolase 1 (EPHX1) polymorphisms and esophageal cancer risk has been investigated in various ethnic populations, but the results have been contradictory. We investigated the association of EPHX1 Tyr113His and ... more

J.J. Hu; Z.T. Wang; B. Li
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Ossification; Polymorphism; Posterior longitudinal ligament; Transforming growth factor-β1

Ossification of the posterior longitudinal ligaments (OPLL) has been considered to be associated with abnormalities of bone metabolism, and transforming growth factor-β1 (TGF-β1) has been demonstrated to affect the bone remodeling process. We investigated two SNPs of the TGF-β1 promoter (-509C>T; rs1800469) and exon 1 (869T>C; rs1982073) in 298 Koreans (98 patients with OPLL and ... more

I.B. Han; A.E. Ropper; Y.J. Jeon; H.S. Park; D.A. Shin; Y.D. Teng; S.U. Kuh; N.K. Kim
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NPP1; Ossification; Polymorphism; Posterior longitudinal ligament; Postoperative progression

Ossification of the posterior longitudinal ligament (OPLL) is a condition of the spine that can cause paralysis by compressing the spinal cord. The aim of this study was to evaluate the possible role of nucleotide pyrophosphatase phosphodiesterase 1 gene (NPP1) polymorphism in the etiology and pathology of the OPLL in Chinese patients. DNA from patients with OPLL (N = 95) and ... more

Z. He; H. Zhu; L. Ding; H. Xiao; D. Chen; F. Xue
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ATP-sensitive potassium channels; Dilated cardiomyopathy; E23K; I337V; Polymorphism

ATP-sensitive potassium channels play an important role in myocardial electrical activity. Genetic disruption of these channels predisposes the myocardium to cardiac diseases. Herein we investigated whether two polymorphisms, E23K and I337V, located in the Kir6.2 subunit of ATP-sensitive potassium channels are associated with dilated cardiomyopathy (DCM) in a Chinese population. Blood was ... more

H.L. Xi; J.F. Liu; L. Li; J. Wan

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