Research Article

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03/17/2014
Association study; H-FABP; Polymorphism; PSMC1; Qinchuan cattle

Growth and carcass traits are economically important quality characteristics of beef cattle and are complex quantitative traits that are controlled by multiple genes. In this study, 2 candidate genes, H-FABP (encoding the heart fatty acid-binding protein) and PSMC1 (encoding the proteasome 26S subunit of ATPase 1) were investigated in Qinchuan beef cattle of China. PCR- ... more

W. Liang; H.L. Zhang; Y. Liu; B.C. Lu; X. Liu; Q. Li; Y. Cao
02/28/2014
Polymorphism; Porcine; Receptor function; TLR3

Toll-like receptor 3 (TLR3) recognizes double-stranded RNA, which is a molecular signature of viruses, and plays a pivotal role in host defense against viral invasion. Polymorphisms in the human TLR3 gene have been shown to affect the receptor function and to be associated with a variety of diseases, suggesting correlations between TLR3 polymorphisms and the disease resistance/ ... more

L. Wang; Y.C. Chen; D.J. Zhang; H.T. Li; D. Liu; X.Q. Yang
06/29/2015
Alzheimer’s disease; Apolipoprotein E; Meta-analysis; Polymorphism; PPARγ

We investigated whether Pro12Ala (C→G) and His447His (C→T) polymorphisms of the peroxisome proliferator-activated receptor gamma (PPARγ) gene are associated with susceptibility to Alzheimer’s disease (AD). We conducted a meta-analysis of the associations between the PPARγ Pro12Ala and His447His polymorphisms and AD in subjects. The meta-analysis was performed according to the ... more

Y.H. Lee; G.G. Song
06/11/2015
GSTT1; Neoplasia; Polymorphism; Pterygium

Pterygium is an inflammatory and degenerative ocular surface disease in which the conjunctiva on the cornea grows to form a fibrous tissue in the shape of a triangle. The disorder may be characterized by cell proliferation, inflammatory processes, fibrosis, angiogenesis, and destruction of the extracellular matrix. The anomaly is considered a degenerative eye disease and is erroneously ... more

G.Mdos Reis; deP.R. Júnior; K.S.Fe Silva; D.A. Rodrigues; M.C.S. Gomes; J.V.M. Martins; I.R. da Costa; G.A. Freitas; K.K.O. Moura
06/11/2015
GST; GSTM1; Polymorphism; Pterygium

The first reports about pterygium date back to Hip­pocrates, and this disease still threatens vision health around the world. Pterygium is a formation of fibrous tissue consisting of highly vascular­ized epithelial and subepithelial tissue that grows excessively and with an abnormal shape on the cornea. Many physical and biological factors are associated with the pathogenesis of pterygium ... more

deP.R. Júnior; G.Mdos Reis; K.S.Fe Silva; D.A. Rodrigues; M.C.S. Gomes; J.V.M. Martins; I.R. da Costa; G.A. Freitas; K.K.V.O. Moura
06/01/2015
Chinese bayberry; EST-SSR; Myrica rubra; Polymorphism; RNA-seq

Most plant expressed sequence tag-simple sequence repeats (EST-SSRs) are not polymorphic, and it is important to learn the characteristics of highly polymorphic EST-SSRs. In this study, 357 compound and 5557 non-compound EST-SSRs, identified from the transcriptome of the Chinese bayberry (Myrica rubra ‘Biqi’), were divided into 11 types based on their characteristics. ... more

S.Y. Zhang; C. Feng; C.J. Xu; C.Q. Zhu; K.S. Chen
05/25/2015
Meta-analysis; Polymorphism; Rheumatoid arthritis; Tumor necrosis factor; Vitiligo

We investigated whether the tumor necrosis factor-a (TNF-α) promoter -238 A/G and -308 A/G polymorphisms are associated with rheumatoid arthritis (RA) and vitiligo susceptibility. MEDLINE and EMBASE databases and a manual search were used to identify articles in which TNF-α polymorphisms were determined in RA or vitiligo patients and controls. Meta-analysis was used to ... more

Y.H. Lee; S.C. Bae
04/22/2015
Meta-analysis; Methylenetetrahydrofolate reductase; Polymorphism; Psoriasis

Previous studies investigating the association between methylenetetrahydrofolate reductase (MTHFR) 677C/T polymorphisms and psoriasis risk have reported inconsistent results. The present meta-analysis aimed to comprehensively evaluate the association between MTHFR 677C/T polymorphism and psoriasis risk. The studies regarding the association between MTHFR 677C/T ... more

J.H. Qi; N. Shi; Y.J. Chen; G. Nie
04/17/2015
Angiotensin-converting enzyme; Meta-analysis; Polymorphism; Sarcoidosis

Previous reports identified an association between sarcoidosis and an insertion/deletion (I/D) polymorphism in angiotensin-converting enzyme. Our meta-analysis of articles published between March 1996 and June 2013 identified studies in the PubMed, EMBASE, and the China National Knowledge Infrastructure databases. We examined whether angiotensin-converting enzyme polymorphisms influence ... more

R. Zhu; L.Q. Bi; H. Kong; S.L. Tilley; H. Wang; W.P. Xie
02/13/2015
cluster analysis; Molecular markers; Opuntia germplasm; Polymorphism; Random amplified polymorphic DNA; Tunisian collection

Opuntia ficus indica is one of the most economically important species in the Cactaceae family. Increased interest in this crop stems from its potential contribution to agricultural diversification, application in the exploitation of marginal lands, and utility as additional income sources for farmers. In Tunisia, O. ficus indica has been affected by drastic genetic ... more

B. Zarroug; G. Baraket; L. Zourgui; S. Souid; S. Hannachi

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