Research Article

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Enteral nutrition; Gastric cancer; Immune function; Preoperative

We studied the effects of enteral nutrition (EN) support initiated 1 week before surgery on postoperative nutritional status, immune function, and inflammatory response in gastric cancer patients. A total of 200 gastric cancer patients were randomly divided into two groups: EN starting 1 week before surgery (study group) and EN starting early after surgery (control group). The two groups ... more

F. Wang; M.X. Hou; X.L. Wu; L.D. Bao; P.D. Dong
06/29/2015
Enteral nutrition; Gastric cancer; Immune function; Intestinal function; Nutritional status

The impact of early enteral nutrition (EEN) on clinical outcomes of gastric cancer patients was investigated. Three hundred pa­tients undergoing gastric cancer surgery from July 2010 to May 2014 were randomly divided into experimental and control groups (n = 150/group). Experimental group patients received enteral nutrition in water during the early postoperative period. Control group ... more

B. Li; H.Y. Liu; S.H. Guo; P. Sun; F.M. Gong; B.Q. Jia
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Anti-proliferation; Gastric cancer; miRNA-199a-3p; mTOR

MicroRNAs (miRNAs) are small non-coding RNAs that regulate the translation of targeted mRNAs. An increasing amount of evidence indicates that miRNAs play important role in cancer pathogenesis, apoptosis, proliferation, and differentiation as oncogenes or tumor suppressors. Recently, miRNA-199a has been shown to be involved in many human cancers, although the role of miRNA-199a-3p in ... more

W. Peng; Z.Y. Chen; L. Wang; Z. Wang; J. Li
12/17/2012
Amazon; Epstein-Barr; Gastric cancer; Polymerase chain reaction; Resection margin

Gastric cancer is one of most frequent causes of death in Brazil. The city of Manaus has one of the highest incidences of this disease in Brazil. The Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that is classified as a group 1 carcinogen by the International Agency for Research on Cancer. We obtained biopsies from 6 control subjects and 10 patients with gastric carcinomas living ... more

P.F. de Aquino; P.C. Carvalho; J.Sda Gama Fischer; A.Q.L. de Souza; J.S. Viana; S.R.S. Chalub; A.D.L. de Souza; M.G.C. Carvalho
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Gastric cancer; Meta-analysis; Polymorphism; susceptibility; XRCC1

Association between the XRCC1 Arg399Gln polymorphism and susceptibility to gastric cancer has been investigated; overall, the results have been inconclusive. We made a meta-analysis of 13 case-control studies, including 3278 cases and 6243 controls. Crude odds ratios (OR) with 95% confidence intervals (95%CI) were used to assess this possible association. We found no evidence of a ... more

B.M. Liu; T.M. Liu; B.S. You; H.Y. You; J. Yang; L. Li; Y.C. He
08/29/2012
DNA methylation; Gastric cancer; LOH; MSI; PAI-1 gene

We explored a possible correlation of genetic instability and CpG methylation in the 5'-flanking region of the PAI-1 gene with clinicopathologic features of gastric cancer in Chinese patients and looked for molecular markers for diagnosing gastric tumor development. Microsatellite instability and loss of heterozygosity of the PAI-1 gene locus D7S515, D7S471 and pai-1 ... more

J. Liu; X. Li; N. Yu; Y.Q. Yang; X. Li; Z.Y. Ye; J.C. Li
08/13/2012
Gastric cancer; Meta-analysis; NQO1 gene; Polymorphism; Risk

The association between the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene C609T polymorphism and gastric cancer has been widely evaluated, yet with conflicting results. Data were available from seven study populations involving 2600 subjects. Overall, comparison of alleles 609T and 609C indicated a significantly increased risk (46%) for gastric cancer (95% confidence interval (95 ... more

Y. Zhang; Z.T. Wang; J. Zhong
12/19/2014
Chromogenic detection; Gastric cancer; Helicobacter pylori; Stomach cancer; Susceptibility gene; TNF-α

TNF 308 gene polymorphism and IL-10 polymorphism provided evidence in diagnosing some types of cancer. We aimed to explore the relation of gene polymorphism with gastric cancer. A total of 360 cases of gastric cancer patients were included in the study. The genotypes GG, GA, and AA of the interleukin-10-1082 gene (IL-10-1082) and the tumor necrosis factor-alpha gene (TNF- ... more

T. Yu; Q. Lu; X.L. Ou; D.Z. Cao; Q. Yu
12/12/2014
Gastric cancer; Meta-analysis; Prognosis; S100A4

The prognostic role of S100A4 in gastric cancer is still under debate. The present meta-analysis aimed to evaluate the relationship between S10A4 levels and the prognosis of gastric cancer. We performed a meta-analysis of published studies assessing the relationship between S100A4 and gastric cancer prognosis. We used the Revman 5.0 software to perform literature retrieval, article ... more

Y. Wang; L.B. Zhou; X.H. Li
01/24/2014
Folate intake; Gastric cancer; Methylenetetrahydrofolate reductase; Polymorphisms

Folic acid and methylenetetrahydrofolate reductase (MTHFR) may both affect the development of human cancer. We conducted a population-based case-control study in a Chinese population to investigate the potential role of folate intake and MTHFR gene polymorphisms in gastric cancer, and their interaction with infection by Helicobacter pylori and tumor location. A total of ... more

J. Chen; L. Yuan; Y.Q. Duan; J.Q. Jiang; R. Zhang; Z.J. Huang; X.R. Xiao

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